{"id":"W2009676237","doi":"10.1139/v03-211","title":"Concerning the mechanism of the Friedländer quinoline synthesis","year":2004,"lang":"en","type":"article","venue":"Canadian Journal of Chemistry","topic":"Analytical Chemistry and Chromatography","field":"Chemistry","cited_by":68,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Chemistry; Aldehyde; Quinoline; Ketone; Adduct; Aldol reaction; Trifluoromethanesulfonate; Aldol condensation; Schiff base; Medicinal chemistry; Toluene; Catalysis; Derivative (finance); Reactivity (psychology); Organic chemistry; Stereochemistry","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001626757,0.0001671858,0.000258891,0.00001802227,0.0001935141,0.00003301103,0.000868018,0.0001773,0.002053795],"category_scores_gemma":[0.0003642206,0.0001041438,0.0003763741,0.0001857927,0.0004441061,0.00005065384,0.00002823824,0.000536247,0.000002226046],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001383969,"about_ca_system_score_gemma":0.00130124,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003051628,"about_ca_topic_score_gemma":0.0001650575,"domain_scores_codex":[0.9988238,0.000009412489,0.0004622604,0.0001220751,0.0002822822,0.0003001956],"domain_scores_gemma":[0.9985141,0.0001033857,0.0004231018,0.0003987485,0.000182086,0.0003786311],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002814848,0.00005122086,0.002414681,0.0004951343,0.0004921263,0.0001481181,0.0007599089,0.0004121776,0.9917289,0.001909706,0.001175006,0.0003848808],"study_design_scores_gemma":[0.0002835917,0.000003487517,0.00005192377,0.0003263629,0.0001065384,0.0003131784,0.00106767,0.00000672529,0.9911684,0.003349577,0.003197795,0.0001246814],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9619399,0.0009510016,0.0001203751,0.001908264,0.00008514013,0.00002146555,0.00004574972,0.000007619376,0.0349205],"genre_scores_gemma":[0.9991264,0.00001973312,0.00004333509,0.0001344203,0.0002907265,0.00000177712,0.000001232253,0.00001769737,0.0003646688],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03718652,"threshold_uncertainty_score":0.9988585,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01135196163106151,"score_gpt":0.1924667733213989,"score_spread":0.1811148116903374,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}