{"id":"W2009778384","doi":"10.1371/journal.pone.0071889","title":"Laulimalide Induces Dose-Dependent Modulation of Microtubule Behaviour in the C. elegans Embryo","year":2013,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Microtubule and mitosis dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research; Fondation pour la Recherche Médicale; University of Alberta","keywords":"Microtubule; Paclitaxel; Cell biology; Caenorhabditis elegans; Tubulin; Embryo; In vivo; Biophysics; Chemistry; Microtubule polymerization; Biology; Biochemistry; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001040246,0.0003332686,0.0002669544,0.0002839935,0.0001896561,0.0002038446,0.0002429441,0.0002921601,0.001065814],"category_scores_gemma":[0.0001842827,0.0001932511,0.0002070077,0.00009099014,0.00020316,0.0001658356,0.0002208427,0.0006246566,0.0002647707],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003838982,"about_ca_system_score_gemma":0.0002039873,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001414418,"about_ca_topic_score_gemma":0.00428484,"domain_scores_codex":[0.9998899,0.00001484937,0.0000146451,0.00002903032,0.0000296161,0.00002202887],"domain_scores_gemma":[0.9997973,0.00006202651,0.00004340893,0.00002119292,0.00003045468,0.00004559533],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005978894,0.00001619097,0.00009595144,0.00002811079,0.00000279091,0.00002841081,0.0000116329,0.00003899381,0.9992066,0.00001436163,0.00002492562,0.0004724207],"study_design_scores_gemma":[0.000008134575,0.0002065778,0.004968951,0.000006878357,0.000005906161,0.00003539015,0.00001628839,0.0004009416,0.9936687,0.00001255455,0.0006644207,0.000005189735],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9944276,0.001272334,0.001334097,0.00009666848,0.00002534398,0.0000672663,0.0006522634,0.0001038087,0.002020566],"genre_scores_gemma":[0.9921663,0.0008467126,0.002930506,0.0001087937,0.000009574615,0.0001166395,0.0005166024,0.00004916293,0.003255768],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001414418,"threshold_uncertainty_score":0.00356555,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01962994342550592,"score_gpt":0.2255271530023027,"score_spread":0.2058972095767968,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}