{"id":"W2009825558","doi":"10.1111/j.1462-5822.2008.01197.x","title":"Differential modulation of innate immune cell functions by the<i>Burkholderia cepacia</i>complex:<i>Burkholderia cenocepacia</i>but not<i>Burkholderia multivorans</i>disrupts maturation and induces necrosis in human dendritic cells","year":2008,"lang":"en","type":"article","venue":"Cellular Microbiology","topic":"Cystic Fibrosis Research Advances","field":"Medicine","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; Child and Family Research Institute","funders":"Genome Prairie; Genome British Columbia; Genome Canada; Cystic Fibrosis Foundation","keywords":"Burkholderia cenocepacia; Biology; Burkholderia cepacia complex; Microbiology; Immune system; Dendritic cell; Burkholderia; Immunology; Bacteria","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001201785,0.0002373538,0.00017917,0.0000721863,0.0000959635,0.0002873739,0.00009801758,0.0002389273,0.0006929329],"category_scores_gemma":[0.0001363985,0.00008556408,0.0001544326,0.00008864368,0.0001498318,0.0001593167,0.0001451209,0.0003351306,0.0001608831],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002122161,"about_ca_system_score_gemma":0.0001356312,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004204183,"about_ca_topic_score_gemma":0.0003940304,"domain_scores_codex":[0.9998322,0.00003939519,0.00001790396,0.00002834014,0.00002778356,0.00005438605],"domain_scores_gemma":[0.9999371,0.00001778468,0.00001353134,0.000007646129,0.000008446325,0.00001546337],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001321091,0.00001875797,0.0002253982,0.00002624509,0.000002273621,0.00002012455,0.000009001458,0.00001790837,0.9991117,0.00001643405,0.000008438727,0.0004116154],"study_design_scores_gemma":[0.00002299816,0.0005357763,0.00873087,0.000006022657,0.00001214339,0.0002473262,0.00003652802,0.0002493758,0.9891958,0.0000215721,0.0009383602,0.000003171883],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9980066,0.00108785,0.0004240585,0.00003478712,0.00001080024,0.00001282898,0.00007965828,0.000006437788,0.0003369632],"genre_scores_gemma":[0.9985573,0.0004877372,0.0004234361,0.00003849869,0.000006534807,0.00001651191,0.0001416748,0.000002881023,0.0003254903],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006929329,"threshold_uncertainty_score":0.002318084,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02029594909294172,"score_gpt":0.2558276205729232,"score_spread":0.2355316714799815,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}