{"id":"W2009825558","doi":"10.1111/j.1462-5822.2008.01197.x","title":"Differential modulation of innate immune cell functions by the<i>Burkholderia cepacia</i>complex:<i>Burkholderia cenocepacia</i>but not<i>Burkholderia multivorans</i>disrupts maturation and induces necrosis in human dendritic cells","year":2008,"lang":"en","type":"article","venue":"Cellular Microbiology","topic":"Cystic Fibrosis Research Advances","field":"Medicine","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; Child and Family Research Institute","funders":"Genome Prairie; Genome British Columbia; Genome Canada; Cystic Fibrosis Foundation","keywords":"Burkholderia cenocepacia; Biology; Burkholderia cepacia complex; Microbiology; Immune system; Dendritic cell; Burkholderia; Immunology; Bacteria","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003146248,0.0005877806,0.001069189,0.0004123422,0.0004852049,0.0000612679,0.000342037,0.0004533236,0.0003786597],"category_scores_gemma":[0.00009433675,0.0005045102,0.0002318796,0.0005770518,0.001272564,0.0002911748,0.0002283135,0.0007069153,0.00003126006],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001576362,"about_ca_system_score_gemma":0.0001202731,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000702665,"about_ca_topic_score_gemma":0.0000936553,"domain_scores_codex":[0.996207,0.0004621745,0.001224274,0.0009172932,0.0002862212,0.0009030498],"domain_scores_gemma":[0.9980844,0.0002590203,0.0004454192,0.0007305334,0.00027049,0.0002101268],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004360334,0.0005053931,0.0007562718,0.0002740023,0.00007776209,0.00003493813,0.001004461,0.00004286133,0.9957989,0.00001649708,0.000785951,0.000266941],"study_design_scores_gemma":[0.003905216,0.0004699744,0.02233086,0.0001195501,0.0001054637,0.0001688307,0.0004141515,0.0004359129,0.9700167,0.00005219486,0.001539696,0.0004414161],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9941143,0.001576494,0.001394332,0.0002739419,0.0005078994,0.001440212,0.0004467283,0.0000804481,0.0001656211],"genre_scores_gemma":[0.9959121,0.0002688337,0.0006775975,0.0001159829,0.0001192914,0.00009678925,0.001767472,0.00008539386,0.0009565348],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02578215,"threshold_uncertainty_score":0.9997407,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02029594909294172,"score_gpt":0.2558276205729232,"score_spread":0.2355316714799815,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}