{"id":"W2009883906","doi":"10.1016/j.str.2015.01.002","title":"Structure of EspB from the ESX-1 Type VII Secretion System and Insights into its Export Mechanism","year":2015,"lang":"en","type":"article","venue":"Structure","topic":"Tuberculosis Research and Epidemiology","field":"Medicine","cited_by":98,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Victoria; Vancouver Hospital and Health Sciences Centre; University of British Columbia","funders":"Canadian Light Source; Howard Hughes Medical Institute","keywords":"Secretion; Virulence; Biology; Cell biology; Cell envelope; Secretory protein; Chemistry; Microbiology; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002571204,0.0005437852,0.0005338284,0.0003775739,0.0004228076,0.001234802,0.0005880982,0.001084539,0.002134125],"category_scores_gemma":[0.0004765749,0.0002557903,0.0005607447,0.0005012923,0.0005285139,0.0009147706,0.000355799,0.001677307,0.001248868],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006412513,"about_ca_system_score_gemma":0.0004807113,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004925489,"about_ca_topic_score_gemma":0.000274224,"domain_scores_codex":[0.9999132,0.0000179127,0.000009845774,0.00002208945,0.000020684,0.00001611319],"domain_scores_gemma":[0.9997554,0.00005330818,0.00005869578,0.00002241589,0.00004450469,0.00006578777],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001742067,0.0001674792,0.003733322,0.0006899277,0.00009703144,0.004904082,0.0006696862,0.005297263,0.947418,0.01777189,0.001862111,0.01564707],"study_design_scores_gemma":[0.0005125157,0.002513484,0.05100892,0.000452973,0.0003373649,0.01199404,0.001932079,0.07510549,0.7299315,0.02639342,0.09951746,0.0003007952],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9556876,0.01104719,0.02201676,0.002392339,0.0002224005,0.00005639024,0.0008597914,0.0001813597,0.007536314],"genre_scores_gemma":[0.9735461,0.003767662,0.009895055,0.0005733132,0.0001336461,0.00003504788,0.003664069,0.0000381994,0.008346826],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002134125,"threshold_uncertainty_score":0.007139325,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02528842637293163,"score_gpt":0.2976319949207529,"score_spread":0.2723435685478213,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}