{"id":"W2009983433","doi":"10.1074/jbc.m109.025643","title":"Rpe65 Isomerase Associates with Membranes through an Electrostatic Interaction with Acidic Phospholipid Headgroups","year":2009,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"IONICS Mass Spectrometry (Canada)","funders":"National Eye Institute; National Institutes of Health","keywords":"RPE65; Retinaldehyde; Opsin; Visual phototransduction; Chemistry; Phosphatidylglycerol; Biochemistry; Phospholipid; Rhodopsin; Phosphatidic acid; Membrane; Retinal; Phosphatidylcholine; Retinal pigment epithelium","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002247086,0.0005802786,0.0002524273,0.0003390258,0.0002910624,0.0004322446,0.0002904611,0.0004804353,0.001033036],"category_scores_gemma":[0.0002523238,0.000260249,0.0004305787,0.0002238268,0.0002566051,0.000439813,0.000571222,0.0006072347,0.0006835144],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004272372,"about_ca_system_score_gemma":0.0002015127,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001236172,"about_ca_topic_score_gemma":0.0008937705,"domain_scores_codex":[0.9997337,0.00003190876,0.00001454871,0.00007199609,0.00008797597,0.00005979904],"domain_scores_gemma":[0.999864,0.0000155889,0.0000535881,0.00001361235,0.00002236856,0.00003075581],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005899614,0.00001411168,0.0004768156,0.00004231438,0.0000191371,0.000112169,0.00003578375,0.00001675589,0.9979314,0.0001136321,0.00003556435,0.001143369],"study_design_scores_gemma":[0.00001624822,0.0001517902,0.01502845,0.00002689582,0.00004518727,0.0007655313,0.0001081556,0.0008679125,0.978348,0.0001700265,0.004451766,0.00002013624],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9813969,0.005816525,0.00887038,0.0003954425,0.00007104974,0.00004778377,0.0001729641,0.0001113473,0.003117594],"genre_scores_gemma":[0.9899822,0.002055168,0.003559282,0.0002923655,0.0000269758,0.00002590613,0.0003722155,0.00002437474,0.003661453],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001236172,"threshold_uncertainty_score":0.003455877,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01175303740980831,"score_gpt":0.2448147155904295,"score_spread":0.2330616781806212,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}