{"id":"W2010061680","doi":"10.1371/journal.pone.0059058","title":"NR5A2 Regulates Lhb and Fshb Transcription in Gonadotrope-Like Cells In Vitro, but Is Dispensable for Gonadotropin Synthesis and Fertility In Vivo","year":2013,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Reproductive Biology and Fertility","field":"Medicine","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; McGill University","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institutes of Health; Canadian Institutes of Health Research; National Institute of Child Health and Human Development; McGill University; University of Virginia","keywords":"Biology; Liver receptor homolog-1; Gonadotropic cell; Transcription factor; Gonadotropin-releasing hormone; Luteinizing hormone; Internal medicine; Gonadotropin; Endocrinology; Cell biology; Hormone; Nuclear receptor; Genetics; Gene; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001682098,0.0004014426,0.000242797,0.0002695429,0.0002482239,0.0004563357,0.0002779273,0.0002134029,0.001725539],"category_scores_gemma":[0.0001570641,0.0002304107,0.0003258932,0.0001619809,0.0002892951,0.0002221101,0.000258595,0.0004116094,0.001327753],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003600106,"about_ca_system_score_gemma":0.0003585305,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002219768,"about_ca_topic_score_gemma":0.004385367,"domain_scores_codex":[0.9997763,0.00002211922,0.00002635274,0.00005966327,0.0000851776,0.00003040831],"domain_scores_gemma":[0.9998596,0.00001879354,0.00003216111,0.00002750049,0.0000159329,0.00004594594],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003612331,0.000005921009,0.0001333168,0.00001577355,0.000002098993,0.00002009816,0.000006015026,0.00001335635,0.9992563,0.00004518921,0.0000286893,0.0004370169],"study_design_scores_gemma":[0.00004807448,0.0001543556,0.01289146,0.00001513123,0.00003219882,0.0007344853,0.00007453004,0.001564255,0.9724159,0.00008527629,0.01197485,0.000009449676],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9665668,0.01101331,0.009468813,0.0003914524,0.0001788911,0.00005647199,0.002339645,0.0003253258,0.009659212],"genre_scores_gemma":[0.9733413,0.002772932,0.006861427,0.0002276166,0.00004104586,0.00004795449,0.003722412,0.0001176415,0.01286767],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002219768,"threshold_uncertainty_score":0.005772471,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03482380591345107,"score_gpt":0.2269529010444009,"score_spread":0.1921290951309498,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}