{"id":"W2010094399","doi":"10.2164/jandrol.05063","title":"DNA Integrity Is Compromised in Protamine‐Deficient Human Sperm","year":2005,"lang":"en","type":"article","venue":"Journal of Andrology","topic":"Sperm and Testicular Function","field":"Medicine","cited_by":259,"is_retracted":false,"has_abstract":true,"ca_institutions":"Mount Sinai Hospital","funders":"","keywords":"Protamine; DNA fragmentation; Sperm; Andrology; DNA damage; DNA; Fragmentation (computing); Male infertility; Chromatin; Biology; Nuclear DNA; Infertility; Molecular biology; Chemistry; Medicine; Genetics; Biochemistry; Apoptosis; Mitochondrial DNA; Gene; Pregnancy; Heparin; Programmed cell death","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003036629,0.00007564139,0.0002863173,0.0001864413,0.00002513388,0.000005303134,0.00004978584,0.00009832221,0.0004819072],"category_scores_gemma":[0.00008586068,0.00005498251,0.00008820681,0.00009603531,0.00005000851,0.00004683102,0.00001186977,0.0004269747,0.00002178099],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007797548,"about_ca_system_score_gemma":0.00006283305,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001333032,"about_ca_topic_score_gemma":0.00001916443,"domain_scores_codex":[0.9992275,0.00003531526,0.0003621659,0.0000891406,0.0001444108,0.0001414896],"domain_scores_gemma":[0.9995335,0.00002529273,0.0001491551,0.00009444753,0.0001193399,0.00007827143],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.002521373,0.003567881,0.6435466,0.0001279213,0.0002023261,0.001357115,0.002372925,0.00009420524,0.3136628,0.0008558473,0.0132359,0.01845512],"study_design_scores_gemma":[0.014666,0.006046423,0.9123899,0.000188499,0.0002016753,0.008337661,0.0001693838,0.001788227,0.02546954,0.0005257179,0.03002228,0.0001947234],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9927167,0.0001869461,0.00009660633,0.004538531,0.0001637821,0.0001426988,5.49766e-7,0.000006333431,0.002147904],"genre_scores_gemma":[0.9977508,0.00001563791,0.0005369395,0.001114935,0.0003915,0.000001555694,0.00000177358,0.000006258192,0.0001806237],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2881933,"threshold_uncertainty_score":0.5276546,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02724119181171762,"score_gpt":0.3036888049524893,"score_spread":0.2764476131407717,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}