{"id":"W2010112859","doi":"10.1002/jcp.21859","title":"E2F4 expression is required for cell cycle progression of normal intestinal crypt cells and colorectal cancer cells","year":2009,"lang":"en","type":"article","venue":"Journal of Cellular Physiology","topic":"Cancer-related Molecular Pathways","field":"Medicine","cited_by":85,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs; Université de Sherbrooke; Cancer Research Society","keywords":"Biology; Cancer research; Cell cycle; Cyclin D1; Cell growth; Cyclin E; Cell biology; Cyclin; Cyclin D; Small hairpin RNA; Cancer cell; Cell culture; Molecular biology; Cell; Cancer; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009126091,0.0002891713,0.0002976723,0.0003700776,0.0001954023,0.0002518047,0.0001526693,0.000223622,0.00138386],"category_scores_gemma":[0.0001356792,0.0001603049,0.0001871123,0.0001565259,0.0001696398,0.0001350172,0.0001792261,0.0002606639,0.0004250474],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003964378,"about_ca_system_score_gemma":0.0002720257,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002129757,"about_ca_topic_score_gemma":0.00176247,"domain_scores_codex":[0.9998913,0.00001647698,0.000009807715,0.00001835933,0.00003031969,0.00003382457],"domain_scores_gemma":[0.9998647,0.00002010138,0.00002942493,0.00002038392,0.00001988668,0.00004549932],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008780607,0.00001383648,0.0002679728,0.00001588258,0.00000253522,0.00006826277,0.000004386097,0.00002690875,0.9988047,0.00003592368,0.00002099823,0.0006508587],"study_design_scores_gemma":[0.00002328008,0.000176017,0.01710292,0.000004389075,0.000009570688,0.0005374617,0.00002968744,0.000807991,0.9770784,0.00003897785,0.004186604,0.000004655582],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9942951,0.001992738,0.001899544,0.00006720727,0.00001757182,0.0000209175,0.0005295624,0.0001134088,0.001064084],"genre_scores_gemma":[0.9923896,0.000824837,0.001472815,0.00002558866,0.000005910975,0.00003677105,0.001349523,0.00002388531,0.003871106],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002129757,"threshold_uncertainty_score":0.004629493,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009623261121629858,"score_gpt":0.2708450404702109,"score_spread":0.261221779348581,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}