{"id":"W2010112859","doi":"10.1002/jcp.21859","title":"E2F4 expression is required for cell cycle progression of normal intestinal crypt cells and colorectal cancer cells","year":2009,"lang":"en","type":"article","venue":"Journal of Cellular Physiology","topic":"Cancer-related Molecular Pathways","field":"Medicine","cited_by":85,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs; Université de Sherbrooke; Cancer Research Society","keywords":"Biology; Cancer research; Cell cycle; Cyclin D1; Cell growth; Cyclin E; Cell biology; Cyclin; Cyclin D; Small hairpin RNA; Cancer cell; Cell culture; Molecular biology; Cell; Cancer; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002439014,0.0002297326,0.000688986,0.0001768503,0.00006681919,0.000008381155,0.0001483227,0.0002351764,0.00008979034],"category_scores_gemma":[0.00003915426,0.0001818222,0.0002707506,0.0001408105,0.0001491421,0.0001088732,0.00005107477,0.000384759,0.000002564976],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008058132,"about_ca_system_score_gemma":0.0002583853,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00000672918,"about_ca_topic_score_gemma":5.350477e-7,"domain_scores_codex":[0.9983031,0.00008806019,0.0007014748,0.0002638707,0.0002904135,0.0003530753],"domain_scores_gemma":[0.9981997,0.00008760652,0.0008962814,0.0001866131,0.000410111,0.0002196862],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003142172,0.000433725,0.0000438625,0.0002055799,0.00004322846,0.00005418925,0.000380764,0.0001458931,0.9895819,0.000006244188,0.002159931,0.00380251],"study_design_scores_gemma":[0.003865215,0.005775917,0.000967705,0.0005777864,0.00019346,0.000105627,0.00006324908,0.000935583,0.9861279,0.0003002142,0.000927368,0.0001600476],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.993896,0.002639614,0.002052938,0.0002518918,0.0004794479,0.0004708653,0.00002056232,0.00001261552,0.0001760516],"genre_scores_gemma":[0.9924356,0.000370557,0.006470376,0.0002052809,0.0004088801,0.000008918966,0.000009044703,0.00002955682,0.00006181408],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005342192,"threshold_uncertainty_score":0.7414493,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009623261121629858,"score_gpt":0.2708450404702109,"score_spread":0.261221779348581,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}