{"id":"W2010173117","doi":"10.1182/blood-2014-11-610592","title":"STAT3: too much may be worse than not enough!","year":2015,"lang":"en","type":"letter","venue":"Blood","topic":"Immunodeficiency and Autoimmune Disorders","field":"Immunology and Microbiology","cited_by":34,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"","keywords":"Cytopenia; Autoimmunity; Gain of function; Immunology; Medicine; Immune system; Mutation; Biology; Genetics; Gene; Bone marrow","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001176038,0.0008768017,0.001164292,0.0004379354,0.00148334,0.002213066,0.00103317,0.0125009,0.009467483],"category_scores_gemma":[0.0053255,0.0003374678,0.0007472012,0.0004145304,0.001668403,0.002976338,0.0006933979,0.01752609,0.008340435],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001880161,"about_ca_system_score_gemma":0.0009888159,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001181425,"about_ca_topic_score_gemma":0.002080087,"domain_scores_codex":[0.9989932,0.0002913468,0.0001170751,0.0001591325,0.0002971427,0.0001420709],"domain_scores_gemma":[0.9981388,0.0009003123,0.0001439034,0.00007554246,0.0003608488,0.0003805706],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007350637,0.00003167496,0.000755826,0.00009690034,0.00001959737,0.005114852,0.000048923,0.00005268822,0.000386727,0.002159675,0.9632616,0.02799799],"study_design_scores_gemma":[0.0001771877,0.000175842,0.001819525,0.0004867388,0.00005471959,0.02351145,0.0003776633,0.0005545941,0.0004692287,0.01404037,0.9582583,0.00007437131],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.0006434586,0.00832502,0.0002200205,0.9479741,0.03941774,0.000008765549,0.00004084225,0.00007986875,0.003290111],"genre_scores_gemma":[0.009008051,0.009109882,0.0004199457,0.7814872,0.1905641,0.00001528513,0.00006270663,0.00004122796,0.0092916],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.0125009,"threshold_uncertainty_score":0.03167188,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02218924157547908,"score_gpt":0.235987582513534,"score_spread":0.2137983409380549,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}