{"id":"W2010181602","doi":"10.1016/j.cell.2014.12.001","title":"Dual Proteolytic Pathways Govern Glycolysis and Immune Competence","year":2014,"lang":"en","type":"article","venue":"Cell","topic":"Diabetes and associated disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":63,"is_retracted":false,"has_abstract":false,"ca_institutions":"Child and Family Research Institute; BC Children's Hospital; University of British Columbia","funders":"National Institute of Allergy and Infectious Diseases; Biotechnology and Biological Sciences Research Council; National Institute for Health and Care Research; Canadian Institutes of Health Research; National Institutes of Health; Wellcome Trust","keywords":"Biology; Glycolysis; Immune system; Competence (human resources); Computational biology; Cell biology; Biochemistry; Genetics; Metabolism","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008959192,0.0000865221,0.0000943682,0.000008861894,0.0000526422,0.00002182747,0.00007151315,0.00007101073,0.00001339813],"category_scores_gemma":[0.00003180071,0.00008164309,0.00004477282,0.0000360876,0.00004492958,0.000001686278,0.00007626885,0.00004366766,0.00001944562],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000004102071,"about_ca_system_score_gemma":0.00001503114,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001617358,"about_ca_topic_score_gemma":0.00000663477,"domain_scores_codex":[0.9994646,0.00002492764,0.00009082248,0.000187964,0.00006380769,0.0001678955],"domain_scores_gemma":[0.9997126,0.000007965897,0.00005115012,0.0001607325,0.00001950157,0.00004807682],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000009668689,0.0000532313,0.001680511,0.0000215305,0.00001779227,6.761107e-7,0.00002934552,0.00001122555,0.9942175,0.00006550601,0.0005895308,0.003303525],"study_design_scores_gemma":[0.001643536,0.0005428609,0.01054322,0.00001952242,0.00004868173,0.000002467433,0.0001922595,0.0009028575,0.9173008,0.0004646515,0.06789912,0.0004400127],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9862629,0.0008018144,0.0001849723,0.00005723503,0.00004831339,0.00009695142,0.00001027684,0.000009977226,0.01252763],"genre_scores_gemma":[0.9982658,0.00006053572,0.0001529757,0.0001702863,0.00005354243,0.00001058177,0.00003658062,0.00001111731,0.001238554],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07691664,"threshold_uncertainty_score":0.3329309,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003384889112009831,"score_gpt":0.170784647282735,"score_spread":0.1673997581707251,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}