{"id":"W2010188939","doi":"10.1016/j.cell.2008.01.039","title":"Stem Cells and Early Lineage Development","year":2008,"lang":"en","type":"article","venue":"Cell","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":321,"is_retracted":false,"has_abstract":false,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"","keywords":"Biology; Induced pluripotent stem cell; Epiblast; Embryonic stem cell; Cell biology; Progenitor cell; Somatic cell; Blastocyst; Stem cell; Embryoid body; Lineage (genetic); Germ layer; Embryo; Genetics; Gastrulation; Embryogenesis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008697069,0.00009310017,0.00007943273,0.00002665466,0.00009002204,0.00001115934,0.0001176058,0.00008242379,0.00001224288],"category_scores_gemma":[0.000001460775,0.00008796035,0.00002529587,0.00003809745,0.00005832676,0.000001667628,0.0001441897,0.0000650641,0.0001098809],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000007715639,"about_ca_system_score_gemma":0.00006693236,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004837743,"about_ca_topic_score_gemma":0.000001601833,"domain_scores_codex":[0.9992789,0.00002576114,0.0001167614,0.0002462291,0.0001204894,0.0002118802],"domain_scores_gemma":[0.9996428,0.000006213119,0.00002569405,0.0001841052,0.00003550675,0.00010571],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001602175,0.00003673896,0.002874331,0.0000247606,0.000008603194,0.00002492507,0.0001081277,0.000005070847,0.9939695,5.53101e-7,0.002179193,0.0007521603],"study_design_scores_gemma":[0.0002554528,0.00006346672,0.003273856,0.000002761095,0.000001475697,0.00001036156,0.00001318267,0.000009227482,0.8607929,3.316157e-7,0.1354788,0.00009824309],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9942412,0.00102065,0.0002474074,0.00001165745,0.00005469007,0.0001130076,0.000002483796,0.000008570223,0.004300283],"genre_scores_gemma":[0.9694906,0.0004241434,0.0008398768,0.0000460693,0.00006442393,0.000008015899,0.000007966099,0.00001528982,0.02910362],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1332996,"threshold_uncertainty_score":0.3586919,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01775760095315483,"score_gpt":0.2281319584575913,"score_spread":0.2103743575044364,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}