{"id":"W2010195934","doi":"10.1016/s0264-410x(01)00088-3","title":"Mucosal immunization of mice using CpG DNA and/or mutants of the heat-labile enterotoxin of Escherichia coli as adjuvants","year":2001,"lang":"en","type":"article","venue":"Vaccine","topic":"Escherichia coli research studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":49,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Ottawa; Parks Canada","funders":"","keywords":"CpG Oligodeoxynucleotide; Toxoid; Cholera toxin; Adjuvant; Heat-labile enterotoxin; Enterotoxin; CpG site; Immunogenicity; Antigen; Microbiology; Mutant; Chemistry; Escherichia coli; Biology; Toxin; Immune system; Molecular biology; Immunization; Immunology; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006951413,0.001700328,0.00106415,0.001114226,0.0004231899,0.0005186922,0.0006188989,0.001511277,0.002040189],"category_scores_gemma":[0.0004423401,0.0005468628,0.0007727417,0.0004029492,0.0006478198,0.0007569066,0.0004432225,0.003099094,0.0007811118],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005346827,"about_ca_system_score_gemma":0.0005122516,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007897094,"about_ca_topic_score_gemma":0.0007719249,"domain_scores_codex":[0.9995416,0.00005555079,0.00003107434,0.0001146715,0.00007999116,0.0001771539],"domain_scores_gemma":[0.9994361,0.00009712451,0.0001389998,0.0001079478,0.00005943878,0.000160383],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001692219,0.0006849772,0.0002525125,0.0001014126,0.00002705683,0.00005786944,0.00005490177,0.0002148446,0.9936851,0.0004946388,0.0001431666,0.002591253],"study_design_scores_gemma":[0.0002492915,0.004690486,0.001414234,0.00003665642,0.00008511438,0.000187751,0.00003958492,0.001114816,0.9899012,0.0002418291,0.002027305,0.00001166219],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9864357,0.001834714,0.005808835,0.0004867852,0.0003484404,0.000321281,0.0009320041,0.0004701232,0.003362036],"genre_scores_gemma":[0.9735774,0.002439134,0.008138221,0.0004534592,0.0001412007,0.0003608082,0.001842316,0.0001221398,0.01292523],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002040189,"threshold_uncertainty_score":0.006825089,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01543075547496812,"score_gpt":0.2874905640695541,"score_spread":0.272059808594586,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}