{"id":"W2010198077","doi":"10.1097/jto.0b013e31824c7bed","title":"Cetuximab Plus Cisplatin, Irinotecan, and Thoracic Radiotherapy as Definitive Treatment for Locally Advanced, Unresectable Esophageal Cancer: A Phase-II Study of The SWOG (S0414)","year":2012,"lang":"en","type":"article","venue":"Journal of Thoracic Oncology","topic":"Esophageal Cancer Research and Treatment","field":"Medicine","cited_by":52,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"National Cancer Institute; Imclone; Presbyterian Historical Society; Bristol-Myers Squibb; U.S. Department of Health and Human Services","keywords":"Medicine; Cetuximab; Irinotecan; Cisplatin; Oncology; Internal medicine; Radiation therapy; Esophageal cancer; Phases of clinical research; Chemotherapy; Cancer; Colorectal cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002215414,0.00167307,0.003678545,0.0009171994,0.0005350946,0.001069189,0.001940096,0.001647509,0.004225562],"category_scores_gemma":[0.001163049,0.001011912,0.002030552,0.0007847209,0.001200581,0.001399432,0.0006284455,0.004327648,0.0009728336],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001104029,"about_ca_system_score_gemma":0.00210734,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001918112,"about_ca_topic_score_gemma":0.006876362,"domain_scores_codex":[0.9993911,0.0003147854,0.00003144195,0.0001070244,0.00005359531,0.0001019999],"domain_scores_gemma":[0.9992293,0.0001057042,0.000109593,0.00007317177,0.00003415222,0.0004480552],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.7230757,0.1084718,0.005392601,0.0008293689,0.002313969,0.0001729598,0.0003979913,0.00460639,0.01402296,0.0003355192,0.003822109,0.1365586],"study_design_scores_gemma":[0.5289592,0.4528364,0.01160312,0.00004719142,0.0009077844,0.0002247376,0.0001105402,0.001439693,0.001859346,0.000210064,0.001752209,0.00004975483],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9942879,0.002280246,0.0002802687,0.0002905414,0.0001540809,0.001146505,0.0004188463,0.00007868366,0.001062948],"genre_scores_gemma":[0.9865096,0.003228672,0.002561051,0.0007541397,0.0001986716,0.001842247,0.001512304,0.00005690681,0.003336413],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004225562,"threshold_uncertainty_score":0.0141359,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05171227114998329,"score_gpt":0.4809221230783653,"score_spread":0.4292098519283821,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}