{"id":"W2010212817","doi":"10.1139/y07-027","title":"Ral-GTPase interacts with the β1 subunit of Na<sup>+</sup>/K<sup>+</sup>-ATPase and is activated upon inhibition of the Na<sup>+</sup>/K<sup>+</sup>pumpThis paper is one of a selection of papers published in this Special Issue, entitled The Cellular and Molecular Basis of Cardiovascular Dysfunction, Dhalla 70th Birthday Tribute.","year":2007,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Ion Transport and Channel Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"","keywords":"GTPase; Ouabain; Guanine nucleotide exchange factor; Protein subunit; Biology; Cell biology; ATPase; GTPase-activating protein; Small GTPase; MAPK/ERK pathway; Signal transduction; Molecular biology; Chemistry; Biochemistry; G protein; Enzyme; Sodium","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.001335921,0.000394341,0.0009239377,0.0004375341,0.0002033845,0.00001614556,0.0002998533,0.000494993,0.003981455],"category_scores_gemma":[0.00009362139,0.0002750532,0.000396097,0.0006459182,0.0008740097,0.00008501439,0.00005724414,0.0005804057,6.841821e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007287333,"about_ca_system_score_gemma":0.000511969,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001575108,"about_ca_topic_score_gemma":0.0004627054,"domain_scores_codex":[0.9968757,0.0007631816,0.001078123,0.000465518,0.0003405777,0.0004769154],"domain_scores_gemma":[0.9975541,0.0001460726,0.0008475893,0.0003730407,0.0008308997,0.0002482681],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002599175,0.0002015894,0.002679269,0.0003308492,0.001805933,0.00002488643,0.004718317,0.01562386,0.9683871,0.00002511354,0.002608792,0.0009951448],"study_design_scores_gemma":[0.003995982,0.001015125,0.003192367,0.0001269831,0.0008053187,0.00006545138,0.001665688,0.001611041,0.9793605,0.0000917066,0.007803878,0.0002659508],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9964023,0.001233438,0.0001140284,0.001285794,0.0001409639,0.000542649,0.0001631975,0.000003244768,0.0001143544],"genre_scores_gemma":[0.9980537,0.0005907321,0.00003628918,0.0006131759,0.0004371756,0.00001253909,0.0001171285,0.00003772391,0.0001015095],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01401282,"threshold_uncertainty_score":0.9999701,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005223274276495641,"score_gpt":0.198614309547761,"score_spread":0.1933910352712654,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}