{"id":"W2010273387","doi":"10.1139/cjc-2012-0552","title":"Multicomponent assembly of 2-amino-4-substituted 4<i>H</i>-chromenes using cyclic Michael donors","year":2013,"lang":"en","type":"article","venue":"Canadian Journal of Chemistry","topic":"Multicomponent Synthesis of Heterocycles","field":"Chemistry","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Malononitrile; Salicylaldehyde; Chemistry; Michael reaction; Catalysis; Nucleophile; Medicinal chemistry; Organic chemistry; Combinatorial chemistry; Stereochemistry; Schiff base","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002207621,0.0006521362,0.0003205573,0.0004523292,0.0002111351,0.0003563501,0.000544927,0.000334869,0.002396487],"category_scores_gemma":[0.0001547635,0.0003650577,0.0002988671,0.0002599055,0.0002031761,0.0003831896,0.0005191559,0.0004391722,0.0009468186],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004247202,"about_ca_system_score_gemma":0.0002354849,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005472834,"about_ca_topic_score_gemma":0.002375282,"domain_scores_codex":[0.9998248,0.00001899993,0.0000112702,0.00005277556,0.00003820336,0.00005383977],"domain_scores_gemma":[0.9999018,0.00001466012,0.00002531607,0.00001395832,0.00001007274,0.00003419924],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006394277,0.00006585661,0.0001162856,0.00006468707,0.00001874877,0.000163854,0.00004724283,0.0005503308,0.9918435,0.0008557207,0.0001403303,0.006069415],"study_design_scores_gemma":[0.00002060266,0.0004145386,0.0004886651,0.000006336987,0.00001643934,0.0001418546,0.00001564031,0.001792667,0.993329,0.0001194993,0.003634867,0.0000199098],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9636801,0.00219772,0.0194,0.00009386346,0.0001198721,0.0002321371,0.0003099041,0.0004513506,0.01351511],"genre_scores_gemma":[0.9734461,0.001131884,0.01836691,0.00006613995,0.00002704657,0.0001344072,0.0001933032,0.00005233998,0.006581896],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002396487,"threshold_uncertainty_score":0.008017063,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02129471987124382,"score_gpt":0.2293814464089774,"score_spread":0.2080867265377336,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}