{"id":"W2010304921","doi":"10.1016/s0163-7258(02)00183-3","title":"Cyclin-dependent kinases as potential targets to improve stroke outcome","year":2002,"lang":"en","type":"review","venue":"Pharmacology & Therapeutics","topic":"Cancer-related Molecular Pathways","field":"Medicine","cited_by":42,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Ottawa","funders":"Canadian Stroke Network","keywords":"Cyclin-dependent kinase; Neuroprotection; Kinase; Cyclin; Cell cycle progression; Stroke (engine); Neuroscience; Cell cycle; Cyclin-dependent kinase 5; Cell biology; Biology; Cancer research; Medicine; Cyclin-dependent kinase 2; Apoptosis; Protein kinase A; Biochemistry; Engineering","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0002967128,0.001022857,0.002803923,0.0005482578,0.0001479886,0.00003829319,0.0005791968,0.001016789,0.002328331],"category_scores_gemma":[0.00001980795,0.0009086549,0.001245923,0.0003566843,0.0001529137,0.00004711759,0.0003010328,0.002031769,0.002586676],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008053099,"about_ca_system_score_gemma":0.0005810974,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002254246,"about_ca_topic_score_gemma":0.000003791931,"domain_scores_codex":[0.9955295,0.0003574085,0.001311064,0.001107183,0.0006422126,0.001052678],"domain_scores_gemma":[0.9977475,0.0001537052,0.0005571278,0.0007694651,0.0002020718,0.0005701705],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002320499,0.0007771646,0.000005742884,0.003665854,0.006043768,0.001919627,0.00008645815,0.00001837599,0.01089262,0.00001101329,0.002881238,0.9734661],"study_design_scores_gemma":[0.002288722,0.0008691916,0.000002108752,0.0006460412,0.0255932,0.000728939,0.00001081176,0.00003855198,0.002197597,0.000008981622,0.9669151,0.0007007659],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000127471,0.9861439,0.0002724692,0.0009378571,0.007000257,0.003701544,0.0003748198,0.0002599072,0.001181729],"genre_scores_gemma":[0.0004049893,0.9783452,0.0002781939,0.01228819,0.001623187,0.0004855433,0.0001452926,0.0003081389,0.006121278],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9727653,"threshold_uncertainty_score":0.9993364,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07432070612785109,"score_gpt":0.4064105527928755,"score_spread":0.3320898466650244,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}