{"id":"W2010315416","doi":"10.1007/s00335-010-9268-4","title":"USP32 is an active, membrane-bound ubiquitin protease overexpressed in breast cancers","year":2010,"lang":"en","type":"article","venue":"Mammalian Genome","topic":"Ubiquitin and proteasome pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":70,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Fondo para la Investigación Científica y Tecnológica; National Cancer Institute; National Institutes of Health; Türkiye Bilimsel ve Teknolojik Araştırma Kurumu; Association of Canadian Universities for Northern Studies","keywords":"Biology; Deubiquitinating enzyme; Ubiquitin; Proteases; Oncogene; Gene silencing; Carcinogenesis; Cancer research; Breast cancer; Cancer; Molecular biology; Cell biology; Gene; Biochemistry; Genetics; Enzyme; Cell cycle","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000242529,0.0002850749,0.0002166965,0.00009235174,0.0001122214,0.00007631715,0.000427933,0.0002935636,0.001178252],"category_scores_gemma":[0.00002515827,0.0002998278,0.00009461976,0.0001443333,0.0001341272,0.00001838199,0.0001264331,0.0003436022,0.00006202998],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004746081,"about_ca_system_score_gemma":0.0002749001,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004643101,"about_ca_topic_score_gemma":0.0007630233,"domain_scores_codex":[0.9982656,0.00009296758,0.0002626577,0.0006515159,0.000188803,0.0005384141],"domain_scores_gemma":[0.9988374,0.000006014347,0.000107836,0.0006908287,0.0000752503,0.0002827308],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002687611,0.00008748101,0.002161995,0.00004670178,0.00002086667,0.00001736008,0.0003482664,0.00001431874,0.9956615,0.0000726161,0.0001549973,0.00114513],"study_design_scores_gemma":[0.001070819,0.0001936193,0.01620021,0.00001454751,0.00001017944,0.00007076743,0.0001552761,0.00003483319,0.941546,0.0001324235,0.0400978,0.0004735948],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9933573,0.00005808187,0.00001756893,0.0002664329,0.0001642813,0.0006415155,0.0005403886,0.00002790302,0.004926547],"genre_scores_gemma":[0.9963185,0.00002441609,0.000424927,0.0008063549,0.0005608191,0.0001924903,0.0002800968,0.00005816896,0.001334278],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05411557,"threshold_uncertainty_score":0.9999454,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01247003833263697,"score_gpt":0.243160175161536,"score_spread":0.230690136828899,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}