{"id":"W2010315416","doi":"10.1007/s00335-010-9268-4","title":"USP32 is an active, membrane-bound ubiquitin protease overexpressed in breast cancers","year":2010,"lang":"en","type":"article","venue":"Mammalian Genome","topic":"Ubiquitin and proteasome pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":70,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Fondo para la Investigación Científica y Tecnológica; National Cancer Institute; National Institutes of Health; Türkiye Bilimsel ve Teknolojik Araştırma Kurumu; Association of Canadian Universities for Northern Studies","keywords":"Biology; Deubiquitinating enzyme; Ubiquitin; Proteases; Oncogene; Gene silencing; Carcinogenesis; Cancer research; Breast cancer; Cancer; Molecular biology; Cell biology; Gene; Biochemistry; Genetics; Enzyme; Cell cycle","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002116525,0.0003232367,0.0002574378,0.0005602695,0.0002457043,0.000341155,0.0001370604,0.0003118642,0.001451876],"category_scores_gemma":[0.0002922924,0.0001797508,0.0001987773,0.0003351468,0.0002453278,0.000192796,0.0002210439,0.0002877268,0.0004141329],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00041305,"about_ca_system_score_gemma":0.0002057446,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006185957,"about_ca_topic_score_gemma":0.000448184,"domain_scores_codex":[0.9999099,0.00001413534,0.0000110595,0.00001571932,0.00003222364,0.00001694062],"domain_scores_gemma":[0.9998918,0.0000156846,0.00002936061,0.00001091841,0.00001418942,0.00003811719],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006879263,0.00002205928,0.004728179,0.00005738336,0.00002717165,0.001841916,0.00003095683,0.0001220701,0.9876238,0.000364861,0.0005507167,0.003943034],"study_design_scores_gemma":[0.0001316267,0.0004392852,0.08437656,0.0000239569,0.0001289637,0.02772397,0.0001982986,0.00319397,0.8625386,0.001046361,0.02017419,0.00002418992],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9950715,0.002447714,0.0008137661,0.0002341463,0.00003387317,0.000009514974,0.0004511349,0.00005425335,0.0008840706],"genre_scores_gemma":[0.9967507,0.0007890783,0.0005118303,0.00002264819,0.00001660017,0.000006079295,0.0005801425,0.000008490731,0.001314393],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001451876,"threshold_uncertainty_score":0.004857004,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01247003833263697,"score_gpt":0.243160175161536,"score_spread":0.230690136828899,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}