{"id":"W2010341554","doi":"10.1158/1538-7445.cec13-a55","title":"Abstract A55: Histone deacetylase inhibitors as differentiation agents in breast cancer cells","year":2013,"lang":"en","type":"article","venue":"Cancer Research","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; McGill University; Institute for Research in Immunology and Cancer","funders":"","keywords":"GATA3; FOXA1; Trichostatin A; Histone deacetylase; Cancer research; Breast cancer; Histone deacetylase inhibitor; Tamoxifen; Estrogen receptor; Transcription factor; Estrogen receptor alpha; Biology; Corepressor; Cancer; Endocrinology; Internal medicine; Histone; Medicine; Nuclear receptor; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001736635,0.0003668545,0.0003815975,0.0004361179,0.0002175598,0.0003453279,0.0002837486,0.0003009926,0.003758164],"category_scores_gemma":[0.00007744419,0.0001281777,0.0003701721,0.000351944,0.0001610318,0.0001396787,0.0002208804,0.0005392761,0.001296353],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004552424,"about_ca_system_score_gemma":0.0004128054,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001463941,"about_ca_topic_score_gemma":0.002149725,"domain_scores_codex":[0.9998744,0.00001450603,0.00001862481,0.00002356765,0.00004128692,0.00002775941],"domain_scores_gemma":[0.9999506,0.000006927316,0.000008955957,0.000006137595,0.00001226953,0.00001511927],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004595778,0.0001350996,0.0002596767,0.0003439711,0.00002358216,0.0001251778,0.00002490164,0.0001230433,0.9666299,0.0006089595,0.001954891,0.02931114],"study_design_scores_gemma":[0.0002007435,0.001628109,0.005791308,0.00004128981,0.00007690242,0.0004204009,0.00003240597,0.0005568836,0.9227131,0.000145043,0.06838097,0.00001288175],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7992334,0.1309421,0.008531059,0.00250903,0.003207441,0.0006152156,0.005139365,0.001183931,0.04863847],"genre_scores_gemma":[0.9073961,0.03959305,0.008975646,0.0008857559,0.0003324626,0.0002920046,0.003948842,0.00006577001,0.03851027],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003758164,"threshold_uncertainty_score":0.01257229,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04175346754463438,"score_gpt":0.3906595533562019,"score_spread":0.3489060858115675,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}