{"id":"W2010348808","doi":"10.1016/j.bbabio.2005.09.006","title":"The mitochondrial channel VDAC has a cation-selective open state","year":2005,"lang":"en","type":"article","venue":"Biochimica et Biophysica Acta (BBA) - Bioenergetics","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":75,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary","funders":"Division of Molecular and Cellular Biosciences; National Institute of General Medical Sciences; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Voltage-dependent anion channel; Gating; Conductance; Chemistry; Ion channel; Membrane potential; Biophysics; Membrane; Bacterial outer membrane; Biochemistry; Physics; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002568851,0.0004624431,0.0003398113,0.00008097151,0.000703709,0.00041414,0.001153991,0.0003128946,0.00002457745],"category_scores_gemma":[0.0001978606,0.0003651765,0.0002413259,0.0003339816,0.0004627919,0.00002670448,0.0005867815,0.0003002119,0.0001161134],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005460348,"about_ca_system_score_gemma":0.0003929915,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009036143,"about_ca_topic_score_gemma":0.0004863071,"domain_scores_codex":[0.9972861,0.0003392971,0.000543228,0.0008872243,0.0002849103,0.0006592168],"domain_scores_gemma":[0.9980598,0.0000794021,0.0003374282,0.0009947693,0.0002984914,0.0002300809],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006315749,0.0002132575,0.0000022919,0.00000546502,0.0001460287,0.000001354262,0.0002885945,0.00007632581,0.9427562,0.00055207,0.0544618,0.0008650212],"study_design_scores_gemma":[0.0009895406,0.0005242279,0.000131435,0.000009243244,0.00004837469,0.0000141463,0.00006623775,0.0001634386,0.7909612,0.0005703169,0.2060852,0.0004365966],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9679649,0.0004952218,0.002796999,0.02085303,0.00334054,0.001468365,0.0003228312,0.0001046254,0.002653473],"genre_scores_gemma":[0.979477,0.001433407,0.004531601,0.002938931,0.00314236,0.0002464248,0.0007452628,0.0001129784,0.007372017],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.151795,"threshold_uncertainty_score":0.99988,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02106184380012007,"score_gpt":0.2714882149461497,"score_spread":0.2504263711460296,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}