{"id":"W2010387596","doi":"10.1371/journal.pone.0095130","title":"SNARE Zippering and Synaptic Strength","year":2014,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research; University of Toronto","keywords":"Tonic (physiology); Neurotransmitter; Biophysics; Neurotoxin; Chemistry; SNARE complex; Synaptic vesicle; Cell biology; Neuroscience; Biology; Receptor; Biochemistry; Exocytosis; Vesicle; Secretion; Membrane","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002161194,0.0001783844,0.0003053006,0.0002935561,0.000133371,0.0003957911,0.000302018,0.0003390116,0.001038749],"category_scores_gemma":[0.0007943882,0.0002431039,0.0001751647,0.0001762979,0.0002581462,0.0004100616,0.0004031603,0.0004694403,0.0003073809],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004065198,"about_ca_system_score_gemma":0.00009570788,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003740467,"about_ca_topic_score_gemma":0.0004958069,"domain_scores_codex":[0.9997334,0.0000231358,0.00002726105,0.00005460091,0.0001133776,0.00004823176],"domain_scores_gemma":[0.9994212,0.0001472263,0.0001818897,0.00007096167,0.00007411974,0.0001045404],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009073877,0.00001488888,0.003546211,0.00001212269,0.00001682932,0.00004862036,0.00001175872,0.0002424824,0.9945133,0.00008849146,0.000008751059,0.001405891],"study_design_scores_gemma":[0.00001769963,0.0004455977,0.3097557,0.000008644623,0.00005457029,0.001161997,0.0000445575,0.008090897,0.679588,0.000473613,0.0003406424,0.00001808797],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9985952,0.0002032465,0.0007005412,0.00001077606,0.000001626856,0.00000484812,0.00007609047,0.00002165032,0.0003860315],"genre_scores_gemma":[0.999435,0.00005505907,0.0002218288,0.000006437295,0.000001021254,0.000003122101,0.00008686653,0.000003777868,0.0001868047],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001038749,"threshold_uncertainty_score":0.00347501,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01357948607498091,"score_gpt":0.1846402819209475,"score_spread":0.1710607958459666,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}