{"id":"W2010479287","doi":"10.1128/iai.73.10.6523-6529.2005","title":"Recombinant Shiga Toxin B-Subunit-Keyhole Limpet Hemocyanin Conjugate Vaccine Protects Mice from Shigatoxemia","year":2005,"lang":"en","type":"article","venue":"Infection and Immunity","topic":"Escherichia coli research studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":50,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary; University of Alberta","funders":"Canadian Institutes of Health Research","keywords":"Keyhole limpet hemocyanin; Immunogenicity; Biology; Shiga toxin; Microbiology; Virology; Recombinant DNA; Antibody; Toxin; Shiga-like toxin; Escherichia coli; Immunology; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003588386,0.0008957637,0.000619464,0.0005727032,0.0001711607,0.0003787471,0.0003613388,0.0009331066,0.0008570922],"category_scores_gemma":[0.0002737303,0.000299879,0.0003023478,0.0001513083,0.0003409284,0.000405493,0.000204603,0.001343784,0.000354591],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002727349,"about_ca_system_score_gemma":0.0003568609,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003559016,"about_ca_topic_score_gemma":0.0003352187,"domain_scores_codex":[0.9997535,0.00003486267,0.00001954217,0.00003804934,0.00004983376,0.0001041848],"domain_scores_gemma":[0.9996941,0.00004653431,0.00007871165,0.00004336387,0.00003429501,0.0001029975],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001731585,0.001442669,0.000318826,0.00006138517,0.00002530692,0.00006717243,0.00003377033,0.0002497073,0.99345,0.0001527828,0.0001070013,0.002359875],"study_design_scores_gemma":[0.0007623801,0.02440264,0.006942269,0.0000568431,0.00008991521,0.0003583733,0.00005615445,0.002554076,0.9620718,0.0002171486,0.002471901,0.00001650806],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9966688,0.0006896934,0.001183403,0.0001385382,0.00006222341,0.00007825858,0.0001720524,0.0001794951,0.0008276107],"genre_scores_gemma":[0.9956975,0.0005392071,0.0009767652,0.0001275792,0.00004027472,0.00008210904,0.0004715045,0.0000321413,0.00203301],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009331066,"threshold_uncertainty_score":0.002867222,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01089809481341535,"score_gpt":0.2612043720030687,"score_spread":0.2503062771896533,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}