{"id":"W2010479287","doi":"10.1128/iai.73.10.6523-6529.2005","title":"Recombinant Shiga Toxin B-Subunit-Keyhole Limpet Hemocyanin Conjugate Vaccine Protects Mice from Shigatoxemia","year":2005,"lang":"en","type":"article","venue":"Infection and Immunity","topic":"Escherichia coli research studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":50,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary; University of Alberta","funders":"Canadian Institutes of Health Research","keywords":"Keyhole limpet hemocyanin; Immunogenicity; Biology; Shiga toxin; Microbiology; Virology; Recombinant DNA; Antibody; Toxin; Shiga-like toxin; Escherichia coli; Immunology; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003303689,0.0001891658,0.0001856787,0.00004837246,0.0003215128,0.0000585047,0.0001209545,0.0001586145,0.0000693292],"category_scores_gemma":[0.000295324,0.0001768724,0.00006023208,0.0001387605,0.00007155315,0.00001790025,0.0002905717,0.0003479098,0.00003291303],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003569629,"about_ca_system_score_gemma":0.00005893236,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001589864,"about_ca_topic_score_gemma":0.001305226,"domain_scores_codex":[0.9988936,0.0002357062,0.0002078782,0.0002783249,0.0001079292,0.0002765277],"domain_scores_gemma":[0.9993189,0.00003581999,0.00008076117,0.0003257283,0.0001240523,0.0001147524],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002021791,0.0002054013,0.02050147,0.00002528553,0.0001134479,0.000001768062,0.0001588959,0.000009814556,0.966645,0.00003280548,0.002261754,0.009842184],"study_design_scores_gemma":[0.002021884,0.0007702387,0.1346349,0.00004956583,0.00002467343,0.00002833859,0.0001381471,0.0002283507,0.666178,0.0001694693,0.1953606,0.0003959355],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9962108,0.0009672208,0.0001327069,0.0006499074,0.0001400517,0.0003207506,0.000013735,0.00004443929,0.001520447],"genre_scores_gemma":[0.9961604,0.001956396,0.0003064975,0.000458036,0.0001951277,0.00006668891,0.00008357721,0.00002099553,0.0007522956],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.300467,"threshold_uncertainty_score":0.7212647,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01089809481341535,"score_gpt":0.2612043720030687,"score_spread":0.2503062771896533,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}