{"id":"W2010480982","doi":"10.1021/bi901780j","title":"Structural and Kinetic Characterization of the LPS Biosynthetic Enzyme <scp>d</scp>-α,β-<scp>d</scp>-Heptose-1,7-bisphosphate Phosphatase (GmhB) from <i>Escherichia coli</i>,","year":2010,"lang":"en","type":"article","venue":"Biochemistry","topic":"Enzyme Structure and Function","field":"Materials Science","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University; McMaster University","funders":"Canadian Institutes of Health Research","keywords":"Heptose; Dephosphorylation; Biosynthesis; Biochemistry; Chemistry; Phosphatase; Escherichia coli; Bacterial outer membrane; Enzyme; Mutant","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001516968,0.0002263416,0.0001221837,0.0001358023,0.0001323507,0.0002860784,0.0002860111,0.00019574,0.0004520708],"category_scores_gemma":[0.0003856908,0.0001384237,0.0001568668,0.0002454406,0.0001907117,0.0002503805,0.0001000146,0.0005162216,0.0002314619],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005555212,"about_ca_system_score_gemma":0.0004113117,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002985997,"about_ca_topic_score_gemma":0.001754562,"domain_scores_codex":[0.9999242,0.000009610412,0.000004680874,0.00001457009,0.00003281407,0.00001423466],"domain_scores_gemma":[0.9998393,0.00003633049,0.00004631432,0.00001835522,0.00003085487,0.00002871732],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003257064,0.0001476808,0.001816606,0.00007148021,0.00001134627,0.00009433911,0.00004446094,0.002067035,0.989258,0.000932737,0.0002633858,0.004967247],"study_design_scores_gemma":[0.00002000402,0.0002121505,0.009438142,0.000006759479,0.00001530816,0.0003235686,0.00004786869,0.01472565,0.9705589,0.0003153271,0.004318507,0.00001780208],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9944491,0.0008181698,0.002836909,0.0001191133,0.00001076512,0.00001096524,0.0006854016,0.00003415072,0.00103543],"genre_scores_gemma":[0.9921217,0.0006465978,0.002896481,0.00002485892,0.000005958198,0.00001119607,0.003036611,0.00002900369,0.001227661],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002985997,"threshold_uncertainty_score":0.005937219,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005089692832441087,"score_gpt":0.1921749305099237,"score_spread":0.1870852376774826,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}