{"id":"W2010480982","doi":"10.1021/bi901780j","title":"Structural and Kinetic Characterization of the LPS Biosynthetic Enzyme <scp>d</scp>-α,β-<scp>d</scp>-Heptose-1,7-bisphosphate Phosphatase (GmhB) from <i>Escherichia coli</i>,","year":2010,"lang":"en","type":"article","venue":"Biochemistry","topic":"Enzyme Structure and Function","field":"Materials Science","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University; McMaster University","funders":"Canadian Institutes of Health Research","keywords":"Heptose; Dephosphorylation; Biosynthesis; Biochemistry; Chemistry; Phosphatase; Escherichia coli; Bacterial outer membrane; Enzyme; Mutant","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002096068,0.000444467,0.0003985479,0.00003617736,0.0002728217,0.0001714442,0.0006032172,0.0004176258,0.0002693825],"category_scores_gemma":[0.0007981587,0.0003457796,0.000126717,0.0003127409,0.0005082278,0.0002253788,0.0002472777,0.0004064808,0.00004279178],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000032845,"about_ca_system_score_gemma":0.0001333706,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001464821,"about_ca_topic_score_gemma":0.00001842408,"domain_scores_codex":[0.9976907,0.00006618923,0.0005429834,0.0007289556,0.0004617143,0.000509508],"domain_scores_gemma":[0.9978987,0.0003050505,0.0005302309,0.0008878967,0.0001511727,0.0002269811],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001248443,0.00002876659,0.001840653,0.00009573169,0.00002061266,0.000002729187,0.0003820827,0.000002654347,0.9960927,0.00009738489,0.001204852,0.0002192849],"study_design_scores_gemma":[0.0005170793,0.00003800601,0.02663356,0.00005746264,0.00009944281,0.0000140945,0.0001938053,0.0001828271,0.965723,0.0001945558,0.006233024,0.0001131808],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9950911,0.0006503224,0.00005062481,0.00006144278,0.002119638,0.0003132962,0.001072862,0.0001129287,0.0005277306],"genre_scores_gemma":[0.9972302,0.00005453583,0.0005129704,0.0002449345,0.0004853767,0.0000249689,0.00037111,0.00005156138,0.001024372],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0303698,"threshold_uncertainty_score":0.9998994,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005089692832441087,"score_gpt":0.1921749305099237,"score_spread":0.1870852376774826,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}