{"id":"W2010490561","doi":"10.1038/sj.bjc.6606053","title":"Attenuated reovirus displays oncolysis with reduced host toxicity","year":2010,"lang":"en","type":"article","venue":"British Journal of Cancer","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":47,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Dalhousie University; University of Calgary","funders":"National Cancer Institute; Fondation pour la Recherche Médicale; Canadian Institutes of Health Research; Terry Fox Foundation; University of Calgary","keywords":"Oncolytic virus; Biology; Virology; Cell culture; In vitro; Cancer cell; Pancreatic cancer; Cancer research; Virus; Cancer; Molecular biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003643661,0.0001149271,0.0002031052,0.00005124632,0.0001005955,0.00007106561,0.0003045608,0.0001224474,0.0002834732],"category_scores_gemma":[0.00008027005,0.0001106722,0.0001112255,0.0001577279,0.0001316274,0.00001001834,0.00004066077,0.0004305007,0.000003869553],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003116449,"about_ca_system_score_gemma":0.000446386,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002264076,"about_ca_topic_score_gemma":0.01298652,"domain_scores_codex":[0.9988647,0.00007030911,0.0002612379,0.0001936574,0.0003450081,0.0002651463],"domain_scores_gemma":[0.9989395,0.00001049507,0.0002110463,0.0002067652,0.0004516151,0.0001806038],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002116048,0.00007672398,0.001811286,0.000006305065,0.0001730642,0.0001327855,0.0000132321,0.00004155049,0.9559113,6.854852e-7,0.002665273,0.03705175],"study_design_scores_gemma":[0.001535402,0.001801017,0.01389363,0.00007809052,0.00004364956,0.0009051674,0.00002017122,0.000009070012,0.9614484,0.000007286344,0.02006714,0.0001909478],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9963266,0.002534452,0.00004785495,0.0003635822,0.0002069523,0.0001003813,0.00004720804,0.000004133628,0.0003688345],"genre_scores_gemma":[0.9960022,0.00198521,0.0002639118,0.0003021413,0.0007773569,0.0000116171,0.000008762058,0.00003218363,0.0006166489],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03686081,"threshold_uncertainty_score":0.7246781,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009718381219689641,"score_gpt":0.300131850537128,"score_spread":0.2904134693174384,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}