{"id":"W2010498205","doi":"10.1038/ni.1645","title":"Toll-like receptor–mediated induction of type I interferon in plasmacytoid dendritic cells requires the rapamycin-sensitive PI(3)K-mTOR-p70S6K pathway","year":2008,"lang":"en","type":"article","venue":"Nature Immunology","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":388,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; National Cancer Institute; National Institutes of Health; National Institute of Diabetes and Digestive and Kidney Diseases; McGill University; Friedrich Miescher Institute for Biomedical Research; Emory University","keywords":"TLR9; PI3K/AKT/mTOR pathway; Biology; Interferon; Plasmacytoid dendritic cell; Cell biology; TLR7; IRF7; RPTOR; Ribosomal protein s6; Toll-like receptor; Cancer research; Signal transduction; Innate immune system; Immunology; P70-S6 Kinase 1; Antigen; Dendritic cell; Immune system; Gene expression; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0108093433545301,"score_gpt":0.2291823551096409,"score_spread":0.2183730117551108,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}