{"id":"W2010502399","doi":"10.2174/1566523054546189","title":"Transcriptionally Targeted Adenovirus Vectors","year":2005,"lang":"en","type":"review","venue":"Current Gene Therapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":75,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Enhancer; Biology; Viral vector; Genetic enhancement; Adenoviridae; Gene; Reporter gene; Gene delivery; Vector (molecular biology); Computational biology; Promoter; Adenovirus genome; Molecular biology; Gene expression; Genetics; Recombinant DNA","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004260569,0.0008412725,0.001119374,0.0002686553,0.0001516724,0.0000677083,0.001066338,0.00046062,0.0007324617],"category_scores_gemma":[0.00001854289,0.0007240837,0.001089298,0.0003686385,0.0001499497,0.000005642189,0.00008106121,0.0006054164,0.0002953784],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001131409,"about_ca_system_score_gemma":0.0009580243,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002547259,"about_ca_topic_score_gemma":0.00002234763,"domain_scores_codex":[0.9964836,0.000489693,0.0007081465,0.001039104,0.0005358758,0.0007435764],"domain_scores_gemma":[0.9982442,0.00002375654,0.0002587298,0.001061758,0.0001466209,0.0002649813],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0004200605,0.0002419519,0.000001213171,0.0004869027,0.0004478831,0.000002588452,0.00002104737,0.000006012122,0.0127651,0.000004391239,0.003542909,0.98206],"study_design_scores_gemma":[0.0007653078,0.001244282,0.000002790046,0.000425884,0.0000959407,0.00002019241,0.000001503908,0.000001330711,0.006028211,0.000009933148,0.9906577,0.0007468635],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001289791,0.9959708,0.00007797386,0.00002721491,0.0009271032,0.001214721,0.0003419927,0.00005709854,0.00009334779],"genre_scores_gemma":[0.0000726672,0.9924515,0.00008257038,0.0001339881,0.00291914,0.0003815203,0.003118583,0.0002262308,0.0006137596],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9871148,"threshold_uncertainty_score":0.999521,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09186519329482874,"score_gpt":0.3912072206450932,"score_spread":0.2993420273502645,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}