{"id":"W2010502399","doi":"10.2174/1566523054546189","title":"Transcriptionally Targeted Adenovirus Vectors","year":2005,"lang":"en","type":"review","venue":"Current Gene Therapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":75,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Enhancer; Biology; Viral vector; Genetic enhancement; Adenoviridae; Gene; Reporter gene; Gene delivery; Vector (molecular biology); Computational biology; Promoter; Adenovirus genome; Molecular biology; Gene expression; Genetics; Recombinant DNA","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005662029,0.0008212713,0.0008803369,0.001196329,0.0002733719,0.001085657,0.001011048,0.0007328716,0.005931694],"category_scores_gemma":[0.0003265484,0.0002992972,0.0003144068,0.001110093,0.0003588339,0.0004774411,0.0004360161,0.001370737,0.01397631],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006606348,"about_ca_system_score_gemma":0.0005383618,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004373011,"about_ca_topic_score_gemma":0.0005468584,"domain_scores_codex":[0.999603,0.00007028947,0.0000396766,0.00007898946,0.0001692938,0.00003871246],"domain_scores_gemma":[0.9998772,0.00002406367,0.00002531419,0.00001653305,0.00003469384,0.00002216141],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002355468,0.000161639,0.0004311523,0.004516037,0.00006743934,0.0006297117,0.0001538753,0.0004521538,0.3562837,0.01893122,0.04593291,0.5722046],"study_design_scores_gemma":[0.00003147972,0.0001045676,0.000327329,0.0002098014,0.00002708214,0.001325977,0.00003183023,0.0001273486,0.04835325,0.001169343,0.9482738,0.00001808112],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0187096,0.7364227,0.1412705,0.001415657,0.003618645,0.001282007,0.006168867,0.003351686,0.08776033],"genre_scores_gemma":[0.06486725,0.7043076,0.112345,0.00137265,0.000539994,0.001186946,0.01216193,0.0002723624,0.1029462],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.005931694,"threshold_uncertainty_score":0.01984352,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09186519329482874,"score_gpt":0.3912072206450932,"score_spread":0.2993420273502645,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}