{"id":"W2010563739","doi":"10.1007/s00424-004-1262-9","title":"Na + /K + pump and endothelial cell survival: [Na + ] i /[K + ] i -independent necrosis triggered by ouabain, and protection against apoptosis mediated by elevation of [Na + ] i","year":2004,"lang":"en","type":"article","venue":"Pflügers Archiv - European Journal of Physiology","topic":"Ion Transport and Channel Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":59,"is_retracted":false,"has_abstract":false,"ca_institutions":"Hôtel-Dieu de Montréal; Montreal Heart Institute; Université de Montréal","funders":"Canadian Institutes of Health Research; Health Canada","keywords":"Ouabain; Apoptosis; Intracellular; Necrosis; Chemistry; Programmed cell death; Molecular biology; Endocrinology; Internal medicine; Pharmacology; Biology; Biochemistry; Medicine; Sodium","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003718153,0.0005149983,0.0005767321,0.0003104471,0.0003801537,0.0005635703,0.0005010281,0.000743699,0.001357554],"category_scores_gemma":[0.000415557,0.0002955308,0.0004784021,0.0003244102,0.0006127645,0.0009997955,0.0003199903,0.001285949,0.0002754621],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006257291,"about_ca_system_score_gemma":0.0006267668,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001362767,"about_ca_topic_score_gemma":0.001728668,"domain_scores_codex":[0.999765,0.00004111024,0.00003740793,0.00003035468,0.00003760645,0.00008853465],"domain_scores_gemma":[0.9998086,0.00002920929,0.00004768616,0.0000343483,0.00002302298,0.00005714181],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.007102116,0.0001979373,0.0006079325,0.0001988503,0.0000353553,0.0004991852,0.0001061825,0.0002179924,0.986533,0.0008514804,0.0001710055,0.00347888],"study_design_scores_gemma":[0.0003651783,0.001545747,0.01063911,0.00001831476,0.0001075541,0.001055708,0.0001442243,0.001387033,0.9819696,0.0004784409,0.002270731,0.00001831338],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9886458,0.006396134,0.002335732,0.0005953228,0.0001002412,0.00003095074,0.0002211657,0.0001179549,0.001556643],"genre_scores_gemma":[0.9947304,0.002055695,0.001232519,0.00009841628,0.00003340162,0.00004185432,0.0002766325,0.00001334339,0.001517695],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001362767,"threshold_uncertainty_score":0.004541457,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007607776529604464,"score_gpt":0.1934717664069616,"score_spread":0.1858639898773571,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}