{"id":"W2010563739","doi":"10.1007/s00424-004-1262-9","title":"Na + /K + pump and endothelial cell survival: [Na + ] i /[K + ] i -independent necrosis triggered by ouabain, and protection against apoptosis mediated by elevation of [Na + ] i","year":2004,"lang":"en","type":"article","venue":"Pflügers Archiv - European Journal of Physiology","topic":"Ion Transport and Channel Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":59,"is_retracted":false,"has_abstract":false,"ca_institutions":"Hôtel-Dieu de Montréal; Montreal Heart Institute; Université de Montréal","funders":"Canadian Institutes of Health Research; Health Canada","keywords":"Ouabain; Apoptosis; Intracellular; Necrosis; Chemistry; Programmed cell death; Molecular biology; Endocrinology; Internal medicine; Pharmacology; Biology; Biochemistry; Medicine; Sodium","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004159996,0.0002005332,0.000308999,0.0001045526,0.00008663425,0.00001439255,0.0001371178,0.00007818695,0.000005011902],"category_scores_gemma":[0.00004085361,0.0001789832,0.0001136132,0.00008595692,0.0001606239,0.00001817743,0.00003741245,0.0001837648,0.000001446248],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001456714,"about_ca_system_score_gemma":0.00004527619,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001673089,"about_ca_topic_score_gemma":0.000001948528,"domain_scores_codex":[0.9984798,0.0003085333,0.0005419507,0.0002749419,0.0001775882,0.0002172314],"domain_scores_gemma":[0.9990357,0.00002065436,0.0005639583,0.0001311482,0.0001268536,0.0001216723],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005287919,0.0001293644,0.0001121516,0.00005115506,0.0000818642,0.000001701619,0.0003058332,0.0001638636,0.995566,0.000004593678,0.00009352511,0.002961216],"study_design_scores_gemma":[0.003061415,0.001150214,0.006236993,0.0000353043,0.00005555615,0.00001182684,0.0001824488,0.00006585802,0.9881807,0.00009964623,0.0007190632,0.0002009475],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9939841,0.0003472588,0.004975921,0.0001319086,0.0001669726,0.0001847069,0.0000758681,0.000007027846,0.0001262513],"genre_scores_gemma":[0.9981255,0.001225284,0.0001294888,0.0000681782,0.0001348267,0.000002752274,0.0002265946,0.00003505302,0.00005232011],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007385213,"threshold_uncertainty_score":0.7298723,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007607776529604464,"score_gpt":0.1934717664069616,"score_spread":0.1858639898773571,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}