{"id":"W2010577903","doi":"10.1371/journal.ppat.0030085","title":"HIV-1 Vpr-Mediated G2 Arrest Involves the DDB1-CUL4AVPRBP E3 Ubiquitin Ligase","year":2007,"lang":"en","type":"article","venue":"PLoS Pathogens","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":185,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Montreal Clinical Research Institute","funders":"","keywords":"DDB1; Ubiquitin ligase; Cullin; Biology; Cell biology; Ubiquitin; Small interfering RNA; DNA ligase; Molecular biology; Cell cycle checkpoint; Cell cycle; RNA; Biochemistry; DNA; Cell; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009031733,0.0005023619,0.0002307303,0.0002621176,0.0002779379,0.0005161946,0.0002290092,0.0002975667,0.0009541766],"category_scores_gemma":[0.00006230968,0.0002156276,0.0002807592,0.0001577475,0.0001903091,0.00022684,0.0002643744,0.0003428661,0.0007658876],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007980482,"about_ca_system_score_gemma":0.0002138619,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001092137,"about_ca_topic_score_gemma":0.0008391149,"domain_scores_codex":[0.9999045,0.00001154693,0.000006358,0.00003139164,0.00001883874,0.00002737695],"domain_scores_gemma":[0.9999655,0.000003629357,0.00001085944,0.000005864078,0.000003800879,0.00001027955],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000768578,0.00001895045,0.0006607582,0.00004392891,0.00001189054,0.000127116,0.00001035997,0.0001736317,0.9966763,0.000223435,0.0001045391,0.00187227],"study_design_scores_gemma":[0.00001617784,0.00007237672,0.01210045,0.000007666718,0.00001389392,0.000731109,0.00002268882,0.002170489,0.9790658,0.0001356602,0.005658178,0.000005486529],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9864153,0.004907687,0.004923908,0.0001525082,0.00002432424,0.00004359668,0.0007087801,0.0002203797,0.002603499],"genre_scores_gemma":[0.9917773,0.001438966,0.001903183,0.00004643368,0.000005893772,0.00002064412,0.0009066762,0.00002485778,0.003876001],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001092137,"threshold_uncertainty_score":0.005790234,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0221488951449244,"score_gpt":0.2518728585103396,"score_spread":0.2297239633654152,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}