{"id":"W2010598858","doi":"10.1016/j.antiviral.2010.03.010","title":"Dengue virus replicons: Production of an interserotypic chimera and cell lines from different species, and establishment of a cell-based fluorescent assay to screen inhibitors, validated by the evaluation of ribavirin's activity","year":2010,"lang":"en","type":"article","venue":"Antiviral Research","topic":"Mosquito-borne diseases and control","field":"Medicine","cited_by":27,"is_retracted":false,"has_abstract":false,"ca_institutions":"Institute of Infection and Immunity","funders":"Agence Nationale de la Recherche","keywords":"Replicon; Dengue virus; Virology; Dengue fever; Biology; Flavivirus; Subgenomic mRNA; Green fluorescent protein; Ribavirin; Virus; Molecular biology; Hepatitis C virus; Gene; RNA; Genetics; Plasmid","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007408582,0.0007490641,0.0004213843,0.0004686773,0.000370432,0.0004676121,0.0005530295,0.0003907189,0.001390853],"category_scores_gemma":[0.0005162533,0.0003679479,0.0005183709,0.0003533816,0.0003754549,0.0003552184,0.0004470785,0.001566555,0.0006721446],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006006609,"about_ca_system_score_gemma":0.0004410334,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009299939,"about_ca_topic_score_gemma":0.001646506,"domain_scores_codex":[0.999522,0.0001054984,0.00008215658,0.00009748531,0.0001335959,0.00005923236],"domain_scores_gemma":[0.9996225,0.0001010607,0.00006388297,0.0001256733,0.00003178907,0.00005513672],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001228105,0.00005946922,0.0001381441,0.00002194044,0.00001247852,0.00003453401,0.00003703775,0.000115316,0.9976714,0.0003959123,0.00009795238,0.00129291],"study_design_scores_gemma":[0.00002829264,0.0002246059,0.0008219544,0.000003733184,0.00002896366,0.0001570084,0.0000202825,0.001051001,0.9940327,0.00007091061,0.003551861,0.00000864135],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.932529,0.000954863,0.05495179,0.0004197979,0.0002193926,0.0006653297,0.005582499,0.0005362977,0.004140936],"genre_scores_gemma":[0.8964045,0.0008277504,0.07426423,0.0001238561,0.00003742757,0.0006412129,0.01916493,0.0003751797,0.00816087],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001390853,"threshold_uncertainty_score":0.004652858,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04848538936427187,"score_gpt":0.3572641395959428,"score_spread":0.3087787502316709,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}