{"id":"W2010598960","doi":"10.1046/j.1432-0436.2000.660206.x","title":"Phosphatidylinositol 3-Kinase is required for adherens junction-dependent mammary epithelial cell spheroid formation","year":2000,"lang":"en","type":"article","venue":"Differentiation","topic":"Wnt/β-catenin signaling in development and cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"Cancer Research Society","keywords":"Adherens junction; Biology; Phosphatidylinositol; Cell biology; Spheroid; Kinase; Cell; Cadherin; Cell culture; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001280785,0.000199326,0.0002952252,0.0003101332,0.0004037224,0.0005925781,0.0002273577,0.0003918262,0.001690554],"category_scores_gemma":[0.0002518765,0.0002858317,0.0002587714,0.000208185,0.000224888,0.0002729282,0.0003028717,0.0006640042,0.001319515],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008189249,"about_ca_system_score_gemma":0.0003999786,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002092749,"about_ca_topic_score_gemma":0.003096613,"domain_scores_codex":[0.9998164,0.00002102808,0.00001907877,0.0000286071,0.00006383062,0.00005108432],"domain_scores_gemma":[0.9997477,0.00004076939,0.00007020752,0.00004727934,0.00002464904,0.00006941459],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006438744,0.00001095573,0.0001252135,0.00001158908,0.000002727593,0.00008989023,0.000008356032,0.00003088542,0.9990764,0.0001425749,0.00005266117,0.000384324],"study_design_scores_gemma":[0.0000151681,0.00002801732,0.007717264,0.000003029572,0.00001203812,0.0004734998,0.00003750551,0.001595949,0.9876018,0.00009831783,0.002412695,0.000004599004],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9904779,0.001178354,0.004036515,0.0002465232,0.00004065036,0.00003249081,0.0008200026,0.0002913112,0.002876342],"genre_scores_gemma":[0.9944782,0.0003729917,0.001207549,0.00005296826,0.000005708843,0.00002143812,0.0008750042,0.00004302209,0.002942987],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002092749,"threshold_uncertainty_score":0.005941749,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009345378750478956,"score_gpt":0.2222790296356548,"score_spread":0.2129336508851758,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}