{"id":"W2010629311","doi":"10.1074/jbc.m303740200","title":"Valproate Induces Replication-independent Active DNA Demethylation","year":2003,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":345,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Replication (statistics); DNA demethylation; DNA replication; Demethylation; Chemistry; DNA; Biology; Genetics; Computational biology; DNA methylation; Virology; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000632342,0.0001276158,0.0001655921,0.00002056335,0.00005881706,0.00001857823,0.0001686413,0.0002925873,0.00007390138],"category_scores_gemma":[0.0009887,0.00009690896,0.0001379889,0.00008193817,0.00005469346,0.000005847341,0.00003232596,0.0001794663,0.000002184761],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002761868,"about_ca_system_score_gemma":0.00008414254,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":5.797548e-7,"about_ca_topic_score_gemma":2.383845e-7,"domain_scores_codex":[0.9989347,0.00009582506,0.0003987114,0.000251123,0.000166366,0.0001532958],"domain_scores_gemma":[0.9988943,0.0000336127,0.0004460964,0.0002590434,0.000260005,0.0001069141],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005809849,0.00007042046,0.00337161,0.000005895463,0.0000418606,0.000002226319,0.00001245922,0.00004231967,0.9933444,0.00002795964,0.00004122384,0.002981585],"study_design_scores_gemma":[0.0003265422,0.0001925553,0.00870443,0.000007067136,0.00001426467,0.00002801369,0.000059004,0.000002763008,0.9760956,0.001192093,0.01325627,0.0001214407],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9933252,0.00126346,0.001847488,0.00007614049,0.00009055484,0.00006383798,0.000004628438,0.000004302451,0.003324328],"genre_scores_gemma":[0.9977598,0.0005874349,0.001147104,0.00004386789,0.0002568908,0.000004187973,0.00003020841,0.000008732368,0.0001617748],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01724878,"threshold_uncertainty_score":0.3951833,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03056553222360561,"score_gpt":0.2869920552509702,"score_spread":0.2564265230273646,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}