{"id":"W2010629311","doi":"10.1074/jbc.m303740200","title":"Valproate Induces Replication-independent Active DNA Demethylation","year":2003,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":345,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Replication (statistics); DNA demethylation; DNA replication; Demethylation; Chemistry; DNA; Biology; Genetics; Computational biology; DNA methylation; Virology; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001025534,0.0003227773,0.0002168825,0.000245508,0.000114928,0.000214813,0.0001523389,0.0002253093,0.00127783],"category_scores_gemma":[0.0001249124,0.0001287177,0.0002904379,0.00009704754,0.0001830504,0.0001481331,0.0002162203,0.0004436283,0.0003134604],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001902237,"about_ca_system_score_gemma":0.000169355,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000303063,"about_ca_topic_score_gemma":0.0005238875,"domain_scores_codex":[0.9998723,0.00002367433,0.00001479943,0.00003927295,0.00003127083,0.00001869646],"domain_scores_gemma":[0.999902,0.00002528109,0.00002793402,0.00001803377,0.000009637926,0.00001712063],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005985069,0.00001084413,0.00005654727,0.00002658943,0.000004805454,0.0000364972,0.000006892205,0.00001982559,0.9986964,0.00006422322,0.00002186186,0.000995797],"study_design_scores_gemma":[0.0000108668,0.0001579244,0.001522403,0.000002630378,0.000007068586,0.0001811823,0.000007078502,0.0001785218,0.9961069,0.00004846005,0.001774696,0.000002132456],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9804905,0.006952127,0.007106988,0.0002043946,0.0001359862,0.00006790446,0.0008618512,0.0002145173,0.003965748],"genre_scores_gemma":[0.9927441,0.00178716,0.00240795,0.00006645754,0.00001835572,0.00002405297,0.000762979,0.00002221911,0.002166816],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00127783,"threshold_uncertainty_score":0.004274786,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03056553222360561,"score_gpt":0.2869920552509702,"score_spread":0.2564265230273646,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}