{"id":"W2010629543","doi":"10.1371/journal.ppat.1004593","title":"DNA Is an Antimicrobial Component of Neutrophil Extracellular Traps","year":2015,"lang":"en","type":"article","venue":"PLoS Pathogens","topic":"Neutrophil, Myeloperoxidase and Oxidative Mechanisms","field":"Immunology and Microbiology","cited_by":248,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Cystic Fibrosis Canada","keywords":"Neutrophil extracellular traps; Antimicrobial; DNA; Microbiology; Cell biology; Biology; Chemistry; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001695808,0.0005311658,0.0003206093,0.0004668641,0.0002955263,0.0004493356,0.0002866351,0.0007079755,0.002393138],"category_scores_gemma":[0.0003055513,0.0001899027,0.0002912495,0.0001969511,0.0002946328,0.0003847595,0.0004092586,0.0005921292,0.001354523],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003629366,"about_ca_system_score_gemma":0.0003285905,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002496863,"about_ca_topic_score_gemma":0.0002479311,"domain_scores_codex":[0.9997388,0.00004216278,0.00001549024,0.00006807736,0.00009846221,0.00003707979],"domain_scores_gemma":[0.9998043,0.00003073837,0.00004864271,0.00001018196,0.00004521887,0.00006102402],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005518665,0.00001298288,0.0001648114,0.000157396,0.000007796549,0.0001303333,0.00001401836,0.00004519404,0.9942526,0.0002348177,0.00009416732,0.004830609],"study_design_scores_gemma":[0.0000291926,0.000527912,0.002750857,0.00005963156,0.00002102985,0.00116724,0.00003266477,0.0004508193,0.9647568,0.0002915275,0.02989395,0.00001829866],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7564965,0.1146506,0.09172089,0.002253775,0.001306461,0.0006486573,0.003712447,0.001376878,0.02783377],"genre_scores_gemma":[0.9394379,0.01252452,0.02509002,0.0008669206,0.0002059783,0.0002169723,0.002452292,0.00005880051,0.01914667],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002393138,"threshold_uncertainty_score":0.008005798,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05567517722831478,"score_gpt":0.2426620199926833,"score_spread":0.1869868427643685,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}