{"id":"W2010629543","doi":"10.1371/journal.ppat.1004593","title":"DNA Is an Antimicrobial Component of Neutrophil Extracellular Traps","year":2015,"lang":"en","type":"article","venue":"PLoS Pathogens","topic":"Neutrophil, Myeloperoxidase and Oxidative Mechanisms","field":"Immunology and Microbiology","cited_by":248,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Cystic Fibrosis Canada","keywords":"Neutrophil extracellular traps; Antimicrobial; DNA; Microbiology; Cell biology; Biology; Chemistry; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002273818,0.0002908626,0.0005056641,0.0001523291,0.0001151129,0.00001184699,0.000358626,0.0002535605,0.0004356403],"category_scores_gemma":[0.0000172015,0.0002634552,0.0001557131,0.0001688021,0.0002158211,0.0001413969,0.000101834,0.0002558698,0.0006245959],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003537005,"about_ca_system_score_gemma":0.00008606759,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004649245,"about_ca_topic_score_gemma":0.000005832236,"domain_scores_codex":[0.9982357,0.0003179253,0.0004403525,0.0004697091,0.00008592794,0.0004503854],"domain_scores_gemma":[0.9989263,0.00003052533,0.0001837405,0.0005515515,0.0002052994,0.0001025526],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001842341,0.0008037256,0.0002141002,0.00002599145,0.0001522399,0.00005572624,0.001452189,0.000003156437,0.994329,0.001120822,0.000894064,0.0007647481],"study_design_scores_gemma":[0.0015943,0.0006423213,0.0003795296,0.0000329863,0.0001196985,0.00006372631,0.0003083019,0.0000116623,0.9873475,0.000269396,0.008934462,0.0002961102],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971207,0.0007741158,0.0002063212,0.0003258687,0.0004525256,0.0003043715,0.0003859013,0.00008831465,0.0003418909],"genre_scores_gemma":[0.9978496,0.0000423885,0.0005344909,0.0003676703,0.00008816135,0.00001353179,0.0002659772,0.00004370675,0.0007945081],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008040398,"threshold_uncertainty_score":0.9999818,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05567517722831478,"score_gpt":0.2426620199926833,"score_spread":0.1869868427643685,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}