{"id":"W2010646007","doi":"10.5966/sctm.2014-0011","title":"Selection Based on FOXA2 Expression Is Not Sufficient to Enrich for Dopamine Neurons From Human Pluripotent Stem Cells","year":2014,"lang":"en","type":"article","venue":"Stem Cells Translational Medicine","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"Stemcell Technologies","funders":"Medicinska Forskningsrådet; Karolinska Institutet; Consejo Nacional de Ciencia y Tecnología; National Institute of Neurological Disorders and Stroke; Medical Research Council; Harvard Stem Cell Institute; Eusko Jaurlaritza","keywords":"Induced pluripotent stem cell; FOXA2; Biology; Embryonic stem cell; Cell biology; Stem cell; Progenitor cell; Cellular differentiation; Neural stem cell; Dopamine; Neuroscience; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003228505,0.0002782787,0.0003210164,0.0001861986,0.0001736001,0.0004448745,0.0001374084,0.0002310747,0.001106662],"category_scores_gemma":[0.0002272405,0.0001820992,0.0002612187,0.0001812112,0.0001976926,0.0002447407,0.0003038754,0.0004187933,0.0005293359],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001607342,"about_ca_system_score_gemma":0.0002528368,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003434829,"about_ca_topic_score_gemma":0.0008793687,"domain_scores_codex":[0.9997315,0.00003847124,0.00002978122,0.00006143643,0.0001001572,0.00003865605],"domain_scores_gemma":[0.9998636,0.00005401802,0.00002217269,0.00002071031,0.00001958144,0.00001988211],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000009383437,0.000004600505,0.0001732674,0.00001853208,0.000003726303,0.00002057266,0.000008703715,0.00001877804,0.9987405,0.00006045143,0.00002585943,0.0009155766],"study_design_scores_gemma":[0.00000739671,0.00006194785,0.00266772,0.000006800873,0.00001978447,0.0002377586,0.00001459725,0.0007336304,0.9912106,0.00005719063,0.004978231,0.000004412214],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9670769,0.002587966,0.02570495,0.0002241297,0.00006797645,0.0001112333,0.0006182436,0.0001671811,0.00344138],"genre_scores_gemma":[0.9706993,0.002129693,0.01745649,0.0002266451,0.00002406331,0.0001355714,0.00222598,0.0001408163,0.006961404],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001106662,"threshold_uncertainty_score":0.003702104,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0238561629634031,"score_gpt":0.277310433362663,"score_spread":0.2534542703992599,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}