{"id":"W2010664444","doi":"10.1089/cbr.2011.1047","title":"Synergistic Tumor Suppression by Adenovirus-Mediated Inhibitor of Growth 4 and Interleukin-24 Gene Cotransfer in Hepatocarcinoma Cells","year":2011,"lang":"en","type":"article","venue":"Cancer Biotherapy and Radiopharmaceuticals","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"Government of Jiangsu Province; National Science Foundation","keywords":"Cancer research; Angiogenesis; Fas ligand; Downregulation and upregulation; Tumor suppressor gene; Biology; Vascular endothelial growth factor; Genetic enhancement; Apoptosis; Cancer; Carcinogenesis; Programmed cell death; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000217393,0.0002502667,0.0003202779,0.0001104349,0.00004838376,0.00001446359,0.0001844896,0.0001774276,0.0001876472],"category_scores_gemma":[0.00001420886,0.0002150595,0.00005685641,0.0001590467,0.0004624679,0.00001114117,0.0000486139,0.0001910974,0.00000150197],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002199665,"about_ca_system_score_gemma":0.00008892065,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007955655,"about_ca_topic_score_gemma":0.00002631083,"domain_scores_codex":[0.9984552,0.0001790173,0.0003462556,0.000482798,0.0001605981,0.0003761794],"domain_scores_gemma":[0.9994113,0.00003849426,0.00006090855,0.0002065326,0.00004994327,0.0002328327],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.005239144,0.0001470787,0.006615228,0.0001174358,0.00009024893,0.0000153873,0.0002438422,9.95592e-7,0.9855575,0.000007802924,0.0003715793,0.001593734],"study_design_scores_gemma":[0.002718414,0.001289096,0.0007429995,0.00005617748,0.00002021644,0.000006333094,0.00002529132,0.0001272709,0.9932465,0.00001666174,0.001497689,0.0002533423],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.961365,0.03757063,0.00009333242,0.0001070378,0.0001662906,0.0003991641,0.0002397013,0.00001031337,0.00004846502],"genre_scores_gemma":[0.9681197,0.03082604,0.0000794659,0.0006867265,0.0001097842,0.00006479483,0.00002614497,0.00004441806,0.00004292183],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007688985,"threshold_uncertainty_score":0.8769871,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02856794852973225,"score_gpt":0.3058836997644912,"score_spread":0.2773157512347589,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}