{"id":"W2010789517","doi":"10.1074/jbc.m600497200","title":"Transgenic Drak2 Overexpression in Mice Leads to Increased T Cell Apoptosis and Compromised Memory T Cell Development","year":2006,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Melanoma and MAPK Pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Hôpital Notre-Dame; Centre Hospitalier de l’Université de Montréal","funders":"Canadian Institutes of Health Research; Heart And Stroke Foundation Of Quebec; Kidney Foundation of Canada; Heart and Stroke Foundation of Canada","keywords":"Biology; T cell; Apoptosis; CD8; IL-2 receptor; Cell biology; Programmed cell death; Molecular biology; Cancer research; Immune system; Immunology; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002335019,0.0001797277,0.0002579184,0.00003003126,0.00004270387,0.00001526489,0.0001972071,0.0002751958,0.00004100976],"category_scores_gemma":[0.0000298793,0.0001361169,0.00009009075,0.00006295428,0.00004452421,0.000003750049,0.00007376494,0.0001768976,0.000002494671],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002802944,"about_ca_system_score_gemma":0.00008955963,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000008941289,"about_ca_topic_score_gemma":0.000001324283,"domain_scores_codex":[0.9988897,0.0000488665,0.0004559545,0.0002513875,0.000123334,0.0002307459],"domain_scores_gemma":[0.9994659,0.00002538168,0.0001766081,0.0001115127,0.00005730728,0.0001633219],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003123254,0.000212308,0.003030896,0.00006889595,0.000005324563,0.000007558104,0.00002206755,0.00002218632,0.9956143,2.927857e-7,0.0005245442,0.0001792583],"study_design_scores_gemma":[0.001416131,0.0002077061,0.003971512,0.00005735107,0.000006621804,0.00002212373,0.00004485501,0.000002500987,0.9918916,0.0000129344,0.002176834,0.0001898269],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9967046,0.0004962891,0.0001385483,0.00003748836,0.00002832344,0.00009413619,0.000007817526,0.000004382227,0.002488394],"genre_scores_gemma":[0.9970012,0.00004325861,0.002341917,0.0001126166,0.0001915173,0.000005955835,0.0000380387,0.000009560668,0.0002559926],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00372274,"threshold_uncertainty_score":0.5550684,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01039291454899875,"score_gpt":0.2100162251155095,"score_spread":0.1996233105665108,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}