{"id":"W2010813611","doi":"10.4161/epi.6.4.14953","title":"Identification of restriction endonucleases sensitive to 5-cytosine methylation at non-CpG sites, including expanded (CAG)n/(CTG)n repeats","year":2011,"lang":"en","type":"article","venue":"Epigenetics","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Institute of Neurological Disorders and Stroke; Canadian Institutes of Health Research","keywords":"CpG site; Biology; DNA methylation; Methylation; Restriction enzyme; Illumina Methylation Assay; Genetics; Epigenetics; Molecular biology; Cytosine; Methylated DNA immunoprecipitation; Methyltransferase; 5-Methylcytosine; DNA; Gene; Gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008656382,0.0007601297,0.0006059989,0.0004923072,0.0001294207,0.0003517981,0.0003927553,0.0006796158,0.001298192],"category_scores_gemma":[0.00130842,0.0003864047,0.0004751855,0.0005126536,0.0002892676,0.0002735245,0.0002358366,0.000844134,0.0008667054],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001720301,"about_ca_system_score_gemma":0.0003742675,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006562912,"about_ca_topic_score_gemma":0.00118065,"domain_scores_codex":[0.9991704,0.0002064034,0.0001026692,0.000207904,0.0001901397,0.0001225031],"domain_scores_gemma":[0.9982546,0.0007836753,0.0003534946,0.0001969873,0.0002804291,0.0001306918],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006197581,0.00002795904,0.0004561539,0.00006760404,0.000009181937,0.00003493098,0.00001220828,0.00002263601,0.9976206,0.00002756914,0.00001252951,0.001646585],"study_design_scores_gemma":[0.000008755647,0.0003459184,0.0102284,0.00001387655,0.00004966324,0.0004874305,0.00002625591,0.0003162798,0.9873383,0.0000407951,0.001138242,0.000006101699],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9401816,0.003964862,0.05169196,0.0001461744,0.00005585434,0.0004011504,0.001297749,0.0001881076,0.002072423],"genre_scores_gemma":[0.8887379,0.002691686,0.09696802,0.0001228448,0.00002299564,0.0002800096,0.007473063,0.0001080524,0.003595502],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001298192,"threshold_uncertainty_score":0.004577994,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04592100741835853,"score_gpt":0.2901670134478245,"score_spread":0.2442460060294659,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}