{"id":"W2010813611","doi":"10.4161/epi.6.4.14953","title":"Identification of restriction endonucleases sensitive to 5-cytosine methylation at non-CpG sites, including expanded (CAG)n/(CTG)n repeats","year":2011,"lang":"en","type":"article","venue":"Epigenetics","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Institute of Neurological Disorders and Stroke; Canadian Institutes of Health Research","keywords":"CpG site; Biology; DNA methylation; Methylation; Restriction enzyme; Illumina Methylation Assay; Genetics; Epigenetics; Molecular biology; Cytosine; Methylated DNA immunoprecipitation; Methyltransferase; 5-Methylcytosine; DNA; Gene; Gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004196346,0.0002148846,0.0002212173,0.0001786023,0.0001646479,0.00001821431,0.0001518095,0.0002070134,0.00002648445],"category_scores_gemma":[0.0003460875,0.0002377156,0.0001074959,0.0002963764,0.00006109043,0.000009402963,0.0002048905,0.00007075781,0.00002527979],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006205905,"about_ca_system_score_gemma":0.00004730225,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007507366,"about_ca_topic_score_gemma":0.0001015162,"domain_scores_codex":[0.9982168,0.0001312346,0.0006244677,0.0005077553,0.000262466,0.0002572617],"domain_scores_gemma":[0.9984909,0.00003600121,0.0003788343,0.0005685354,0.0003879737,0.0001377756],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001565176,0.00008595255,0.009035183,0.00001875673,0.00004404268,0.000001867109,0.0004789588,0.0005135909,0.9860932,0.00004807305,0.0001324969,0.003391419],"study_design_scores_gemma":[0.0003090235,0.0004108957,0.07795011,0.0000170752,0.00005677994,0.000001951568,0.00008475587,0.0003122518,0.9194614,0.000242314,0.000923859,0.0002295914],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9549811,0.0005126509,0.04275808,0.00003225981,0.0002453165,0.0004049093,0.00005143361,0.00001985815,0.0009944114],"genre_scores_gemma":[0.9944145,0.0009437436,0.003681579,0.00004264668,0.0001998228,0.00003179436,0.0002790431,0.000043685,0.0003632046],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06891492,"threshold_uncertainty_score":0.969376,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04592100741835853,"score_gpt":0.2901670134478245,"score_spread":0.2442460060294659,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}