{"id":"W2010846406","doi":"10.1097/00002030-200403050-00003","title":"Factors related to loss of HIV-specific cytotoxic T lymphocyte activity","year":2004,"lang":"en","type":"article","venue":"AIDS","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"Memorial University of Newfoundland","funders":"National Institute of Allergy and Infectious Diseases","keywords":"CTL*; Cytotoxic T cell; CD8; Immunology; Biology; T lymphocyte; Viral load; Virology; Viral replication; CD28; T cell; Cellular immunity; Virus; Medicine; Antigen; Immune system; In vitro; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00008435754,0.000127446,0.0002189115,0.0001166626,0.00008432194,0.000004925316,0.0001460012,0.0001400778,0.0006488883],"category_scores_gemma":[0.00002954872,0.00009675903,0.00008987605,0.0002162826,0.000134003,0.00005634259,0.00006349073,0.0001269924,0.003862128],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001777307,"about_ca_system_score_gemma":0.00009425217,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000118829,"about_ca_topic_score_gemma":0.000007474835,"domain_scores_codex":[0.9992032,0.00007735035,0.0001416133,0.0002144494,0.00004223243,0.0003211748],"domain_scores_gemma":[0.9995307,0.00006545874,0.00003803084,0.0002815287,0.00003546877,0.00004876359],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000351882,0.0005634436,0.04103479,0.00001079693,0.0004039558,0.00004012804,0.001065762,0.00004680553,0.943342,0.001614766,0.0007054783,0.01082021],"study_design_scores_gemma":[0.002596492,0.000724763,0.1140296,0.0000195629,0.00001177395,0.00001498149,0.00008191833,4.761219e-8,0.870351,0.0002115693,0.01184237,0.0001159362],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974942,0.0005720243,0.0001154932,0.0001297603,0.000149428,0.0002072744,0.0001179023,0.00004391317,0.001169967],"genre_scores_gemma":[0.9977353,0.00006912386,0.00005555078,0.00001249731,0.000004346794,0.00001280925,0.00008886674,0.00001091905,0.002010611],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07299484,"threshold_uncertainty_score":0.9969135,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02211785838543739,"score_gpt":0.2693531215469147,"score_spread":0.2472352631614773,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}