{"id":"W2010857804","doi":"10.1139/o04-131","title":"Intermediate studies on refolding of arginine kinase denatured by guanidine hydrochloride","year":2005,"lang":"en","type":"article","venue":"Biochemistry and Cell Biology","topic":"Enzyme Structure and Function","field":"Materials Science","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Directorate for Biological Sciences","keywords":"Guanidine; Chemistry; Circular dichroism; Fluorescence; Hydrochloride; Arginine kinase; Molten globule; Protein secondary structure; Protein folding; Native state; Crystallography; Arginine; Folding (DSP implementation); Protein tertiary structure; Stereochemistry; Amino acid; Biochemistry","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002723077,0.0004415003,0.0004526665,0.0002026636,0.0001531762,0.0003346357,0.0003200587,0.0002837543,0.0004604707],"category_scores_gemma":[0.0004519993,0.0001297512,0.0004539839,0.000169806,0.000168009,0.0005027997,0.0002097135,0.0009058585,0.0001489958],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003171095,"about_ca_system_score_gemma":0.0001410751,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009541688,"about_ca_topic_score_gemma":0.000484923,"domain_scores_codex":[0.9997962,0.00002781995,0.00002087323,0.00005997463,0.00004832623,0.00004693857],"domain_scores_gemma":[0.9997666,0.00006037082,0.00005044618,0.00001715206,0.00006321705,0.00004223563],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001280731,0.00003582431,0.0002182304,0.00003992845,0.00000814588,0.00005697351,0.00008035587,0.0001485845,0.9984595,0.0000723972,0.00001128384,0.0007409055],"study_design_scores_gemma":[0.00001096272,0.0005592642,0.003715467,0.00001197524,0.00002152138,0.0001005552,0.00005103133,0.001699971,0.9926829,0.0001220106,0.001007866,0.00001656584],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9884588,0.001684817,0.008605586,0.00004023829,0.00002657555,0.00004768191,0.0002318181,0.00009580387,0.0008087362],"genre_scores_gemma":[0.9891865,0.0007489684,0.008125732,0.00005276807,0.00001083565,0.00005351574,0.0006948706,0.00003652952,0.001090292],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009541688,"threshold_uncertainty_score":0.002300799,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008900660378983268,"score_gpt":0.2475039898441303,"score_spread":0.2386033294651471,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}