{"id":"W2010877704","doi":"10.1016/s0027-5107(00)00121-4","title":"Mutagenicity in lung of Big Blue® mice and induction of tandem-base substitutions in Salmonella by the air pollutant peroxyacetyl nitrate (PAN): predicted formation of intrastrand cross-links","year":2000,"lang":"en","type":"article","venue":"Mutation research. Fundamental and molecular mechanisms of mutagenesis","topic":"Carcinogens and Genotoxicity Assessment","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Victoria","funders":"U.S. Food and Drug Administration; U.S. Environmental Protection Agency","keywords":"Chemistry; Peroxyacetyl nitrate; Mutant; Mutagenesis; Stereochemistry; Biochemistry; Molecular biology; Gene; Biology; Organic chemistry; NOx","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007882272,0.0001398113,0.0002356137,0.0002065139,0.00008219577,0.00001413269,0.0001136419,0.0001881648,0.00001879157],"category_scores_gemma":[0.00003760545,0.000126339,0.00006915185,0.0003533455,0.0003924783,0.00001996576,0.00006379664,0.0001571896,1.068294e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003983601,"about_ca_system_score_gemma":0.0001041054,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009490917,"about_ca_topic_score_gemma":0.0003545326,"domain_scores_codex":[0.9983372,0.0002605227,0.0005492995,0.0002690947,0.0003699071,0.0002139836],"domain_scores_gemma":[0.9994121,0.00003330554,0.0001683801,0.0001731756,0.0001542046,0.00005887872],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000332946,0.0002558841,0.0008779586,0.0001752684,0.00004575335,0.000004998177,0.0004993372,0.001468509,0.9932238,0.0001209572,0.000003354464,0.002991275],"study_design_scores_gemma":[0.001472525,0.0004789669,0.01533194,0.00006113367,0.00002919516,0.00002139861,0.001443212,0.00146763,0.979312,0.0002760933,0.000006223676,0.00009970291],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9928591,0.0008887187,0.005137193,0.00008493008,0.00001969486,0.0006207875,0.0003579125,0.00000259524,0.00002912456],"genre_scores_gemma":[0.9987867,0.0005914065,0.0003860712,0.00002199661,0.000006996153,0.00003378352,0.0001429698,0.00001195528,0.00001811132],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01445398,"threshold_uncertainty_score":0.5151955,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01684802352232452,"score_gpt":0.2910776926957891,"score_spread":0.2742296691734646,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}