{"id":"W2010884756","doi":"10.1007/s10870-014-0552-0","title":"Syntheses and Crystal Structures of Four Novel Thiophene/Phenyl-Piperidine Hybrid Chalcones","year":2014,"lang":"en","type":"article","venue":"Journal of Chemical Crystallography","topic":"Synthesis and biological activity","field":"Chemistry","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Piperidine; Thiophene; Chemistry; Hydrogen bond; Crystal structure; Benzene; Cyclohexane conformation; Ring (chemistry); Molecule; Stereochemistry; Aromaticity; Organometallic chemistry; Crystallography; Medicinal chemistry; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009858488,0.0002431946,0.0002382878,0.0002641437,0.0002485052,0.0003382276,0.0004453823,0.0001829595,0.003323894],"category_scores_gemma":[0.0001631752,0.0001837562,0.0001054923,0.0005871324,0.0001730547,0.0001973189,0.0001499263,0.0004725746,0.0006709174],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004839016,"about_ca_system_score_gemma":0.0004322735,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001438726,"about_ca_topic_score_gemma":0.004216923,"domain_scores_codex":[0.9999431,0.000007069014,0.00000525724,0.000008823518,0.00002247426,0.00001317524],"domain_scores_gemma":[0.9999218,0.00001111198,0.00001386549,0.0000116197,0.00001948725,0.00002218722],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002960076,0.0001092988,0.0004194973,0.0002663801,0.0000248377,0.0003928014,0.0001048729,0.003406933,0.9732574,0.001834196,0.001491326,0.01839654],"study_design_scores_gemma":[0.0001484034,0.0005279017,0.001885032,0.00001527051,0.00003049624,0.000370767,0.0000911306,0.005908843,0.9744123,0.0002141511,0.01636637,0.0000291965],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9818028,0.001573284,0.008177644,0.0001628974,0.00004518939,0.0001354176,0.00158514,0.0003053109,0.006212375],"genre_scores_gemma":[0.9722075,0.001775367,0.01542081,0.00005819278,0.00001311233,0.0001317561,0.002760974,0.0000521681,0.007580095],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003323894,"threshold_uncertainty_score":0.01111948,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02003000865432576,"score_gpt":0.2146296310290181,"score_spread":0.1945996223746924,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}