{"id":"W2010917826","doi":"10.2196/resprot.4462","title":"Timing of High-Dose Rate Brachytherapy With External Beam Radiotherapy in Intermediate and High-Risk Localized Prostate CAncer (THEPCA) Patients and Its Effects on Toxicity and Quality of Life: Protocol of a Randomized Feasibility Trial","year":2015,"lang":"en","type":"article","venue":"JMIR Research Protocols","topic":"Prostate Cancer Diagnosis and Treatment","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Brachytherapy; Medicine; Prostate cancer; External beam radiotherapy; Radiation therapy; Genitourinary system; Prostate; Cancer; Radiology; Randomized controlled trial; Oncology; Urology; Internal medicine","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01858552,0.004055291,0.005866125,0.001253043,0.001778928,0.00250722,0.002577539,0.004221383,0.01901063],"category_scores_gemma":[0.01282561,0.001565173,0.004601095,0.002032915,0.00297494,0.002107769,0.001717645,0.004132351,0.003503752],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002949533,"about_ca_system_score_gemma":0.00967044,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001669794,"about_ca_topic_score_gemma":0.002906215,"domain_scores_codex":[0.9910831,0.005588405,0.000751897,0.0008185017,0.0007303764,0.001027702],"domain_scores_gemma":[0.9905116,0.002071298,0.002857675,0.001136764,0.001714289,0.001708342],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9767433,0.01199908,0.0008103573,0.001479621,0.0008354029,0.00005724186,0.0001249855,0.0007352408,0.001125393,0.0002506125,0.001019803,0.004818952],"study_design_scores_gemma":[0.9169298,0.07585605,0.001910432,0.0002036716,0.0005047246,0.00003562216,0.00006374736,0.0004359026,0.00034916,0.0003825717,0.003299559,0.00002884174],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"protocol","genre_gemma":"protocol","genre_scores_codex":[0.06779083,0.0007794644,0.001777663,0.0003707651,0.0004135285,0.9244456,0.001989344,0.0001130777,0.002319837],"genre_scores_gemma":[0.05122187,0.0005559003,0.00342956,0.0004171788,0.000191303,0.9421039,0.0007877767,0.00001482917,0.001277605],"genre_candidate":"protocol","genre_consensus":"protocol","teacher_disagreement_score":0.01901063,"threshold_uncertainty_score":0.0982908,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1274649680748676,"score_gpt":0.4910220445377369,"score_spread":0.3635570764628693,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}