{"id":"W2010924137","doi":"10.1097/00000542-200308000-00010","title":"Protocol for the Sequence Analysis of Ryanodine Receptor Subtype 1 Gene Transcripts from Human Leukocytes","year":2003,"lang":"en","type":"article","venue":"Anesthesiology","topic":"Ion channel regulation and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Medical Research Council; Medical Research Council Canada","keywords":"RYR1; Complementary DNA; Exon; Central core disease; Biology; Malignant hyperthermia; Gene; Rapid amplification of cDNA ends; Molecular biology; Ryanodine receptor; Genetics; Sequence analysis; Medicine; Pathology; Receptor; Molecular cloning","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001400658,0.002361235,0.001690785,0.002765946,0.00189039,0.0007518905,0.001872605,0.001272766,0.03085731],"category_scores_gemma":[0.001884627,0.001518518,0.001695267,0.002293376,0.0006398845,0.0005835749,0.0009752542,0.003171864,0.03050436],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004424964,"about_ca_system_score_gemma":0.001940338,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000911838,"about_ca_topic_score_gemma":0.002143886,"domain_scores_codex":[0.998553,0.0003865364,0.0002522712,0.0003543974,0.0002374236,0.0002163206],"domain_scores_gemma":[0.9988017,0.0002976024,0.00006796687,0.0003999575,0.0003227345,0.0001099856],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0006900673,0.0002907405,0.0004038781,0.001178766,0.00008801194,0.0012369,0.0002751384,0.0005615464,0.9650472,0.001923803,0.009143764,0.01916021],"study_design_scores_gemma":[0.001327992,0.002849142,0.01238471,0.0008435475,0.0007990524,0.0048738,0.0002551958,0.00477118,0.3890967,0.003917212,0.5785542,0.0003273006],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"methods","genre_gemma":"protocol","genre_scores_codex":[0.04726086,0.008069628,0.8434797,0.00116369,0.002230934,0.02727905,0.03142726,0.004708723,0.03438013],"genre_scores_gemma":[0.04467484,0.00701612,0.7487147,0.001550119,0.0004825755,0.06640568,0.0994887,0.001393126,0.03027425],"genre_candidate":"protocol","genre_consensus":null,"teacher_disagreement_score":0.03085731,"threshold_uncertainty_score":0.1032279,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06270302982322444,"score_gpt":0.3188756847933463,"score_spread":0.2561726549701218,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}