{"id":"W2010943625","doi":"10.1016/j.vetimm.2008.02.007","title":"Attenuated cytokine responses in porcine lymph node cells stimulated with CpG DNA are associated with low frequency of IFNα-producing cells and TLR9 mRNA expression","year":2008,"lang":"en","type":"article","venue":"Veterinary Immunology and Immunopathology","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":17,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Saskatchewan","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Health; Canada Research Chairs","keywords":"TLR9; CpG Oligodeoxynucleotide; Biology; CpG site; Immune system; Peripheral blood mononuclear cell; Spleen; Immunology; Cytokine; Lymph node; Molecular biology; In vitro; DNA methylation; Gene expression; Gene; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002429269,0.0005703401,0.0004810475,0.000244664,0.0001797702,0.0003510082,0.0001403648,0.0005133002,0.003530544],"category_scores_gemma":[0.000276861,0.0002314742,0.0003815833,0.0001361227,0.0003541979,0.0002491318,0.0002210995,0.001268178,0.001092557],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001454258,"about_ca_system_score_gemma":0.000168709,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002254892,"about_ca_topic_score_gemma":0.0002349527,"domain_scores_codex":[0.9997208,0.00005576506,0.00002805416,0.00006037806,0.00004716148,0.00008786138],"domain_scores_gemma":[0.9997104,0.000122283,0.00004183004,0.00004765084,0.00002423457,0.00005366123],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003335642,0.00002434586,0.000171693,0.00003057802,0.000001423859,0.00006057237,0.0000153308,0.00001331809,0.9991069,0.00000728626,0.000008494302,0.000226384],"study_design_scores_gemma":[0.00006500485,0.002081168,0.01570033,0.00001532542,0.0000248078,0.0006286451,0.0001556843,0.0003813424,0.9799486,0.00006402812,0.0009271384,0.000007976818],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9959099,0.0004899221,0.001540463,0.00006899176,0.00008571526,0.00004554305,0.0004833926,0.0000339358,0.001342129],"genre_scores_gemma":[0.994112,0.0004045385,0.001329914,0.0001454239,0.00005267175,0.0001064246,0.001022151,0.00002340752,0.0028037],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003530544,"threshold_uncertainty_score":0.01181078,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01280484497286067,"score_gpt":0.2176056309452547,"score_spread":0.2048007859723941,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}