{"id":"W2010946839","doi":"10.1016/j.peptides.2011.07.017","title":"Discovery and development of a synthetic peptide derived from lactoferrin for clinical use","year":2011,"lang":"en","type":"review","venue":"Peptides","topic":"Antimicrobial Peptides and Activities","field":"Immunology and Microbiology","cited_by":89,"is_retracted":false,"has_abstract":false,"ca_institutions":"NAEJA-RGM Pharmaceuticals (Canada)","funders":"","keywords":"Lactoferrin; Antimicrobial; Antibiotics; Antimicrobial peptides; Clinical trial; Medicine; Intensive care medicine; Pharmacology; Biology; Microbiology; Internal medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002978396,0.0005051841,0.00225608,0.0001189536,0.0001541896,0.00004932177,0.0002906799,0.0006189014,0.00009413296],"category_scores_gemma":[0.0002388464,0.0003897357,0.000564263,0.00004377108,0.0005825752,0.0002289944,0.0002721411,0.0003758641,0.00008823015],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003136256,"about_ca_system_score_gemma":0.0003205156,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001797574,"about_ca_topic_score_gemma":0.0001156045,"domain_scores_codex":[0.9975316,0.0002451561,0.001203302,0.000614484,0.00002561296,0.0003798697],"domain_scores_gemma":[0.9970406,0.001778833,0.0007128209,0.0003790752,0.00005562276,0.00003299575],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001697323,0.0003029674,0.0003499466,0.00526527,0.002079688,0.000002817379,0.000665737,2.763507e-8,0.0009810636,0.0002814746,0.002496531,0.9874048],"study_design_scores_gemma":[0.0004345399,0.00009727493,0.0004169451,0.006303957,0.0006789452,0.00001540274,0.0001434454,6.214613e-8,0.001056941,0.00006166721,0.9902917,0.000499088],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01532978,0.9818714,0.0005880303,0.000003916779,0.0005442257,0.0007732322,0.0007773386,0.00004258508,0.00006951674],"genre_scores_gemma":[0.002053794,0.9895954,0.005123442,0.00002412172,0.0000735676,0.0001001376,0.0006236282,0.00007193265,0.002333998],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9877952,"threshold_uncertainty_score":0.9998555,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1588208248112416,"score_gpt":0.3475980628071726,"score_spread":0.188777237995931,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}