{"id":"W2010987904","doi":"10.1007/s00005-009-0048-3","title":"CD40-activated B cells from patients with systemic lupus erythematosus can be modulated by therapeutic immunoglobulins in vitro","year":2009,"lang":"en","type":"article","venue":"Archivum Immunologiae et Therapiae Experimentalis","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval; Centre Hospitalier Universitaire de Sherbrooke; Université de Sherbrooke; Héma-Québec","funders":"Tenovus","keywords":"CD40; CD154; Antibody; Immunology; CD19; CD38; B cell; Flow cytometry; Naive B cell; B-1 cell; Biology; In vitro; Cytotoxic T cell; Cell biology; Stem cell; CD34","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003247438,0.0005320333,0.0003936182,0.0003420426,0.000189317,0.0002953691,0.0001994258,0.0003999454,0.004304621],"category_scores_gemma":[0.0003346322,0.0001742379,0.0003381098,0.0002605293,0.0001272358,0.0001498558,0.0003093082,0.0008017313,0.001788147],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001374385,"about_ca_system_score_gemma":0.0001686585,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002706553,"about_ca_topic_score_gemma":0.0002857157,"domain_scores_codex":[0.9996287,0.0001274916,0.0000354918,0.00005175302,0.00007572184,0.00008085423],"domain_scores_gemma":[0.9997925,0.00007338365,0.00002158778,0.0000370035,0.00002544446,0.00005011594],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001167168,0.0003743715,0.000983035,0.0001726081,0.0000246522,0.0002665728,0.0001187504,0.0001385364,0.9902884,0.00007154136,0.0002615988,0.006132787],"study_design_scores_gemma":[0.0008203402,0.009240893,0.04142482,0.0001064037,0.0002251175,0.00386733,0.0001703394,0.001910508,0.9189562,0.0002732977,0.0229801,0.00002475276],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9884151,0.005816887,0.00124525,0.0001211059,0.0001069931,0.00009485389,0.0007090546,0.00008820621,0.00340256],"genre_scores_gemma":[0.9907895,0.00200134,0.001021279,0.000118605,0.00008811094,0.0001612147,0.003161195,0.00002449271,0.002634349],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004304621,"threshold_uncertainty_score":0.01440036,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00864120356691489,"score_gpt":0.2204643038771317,"score_spread":0.2118231003102168,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}