{"id":"W2011098763","doi":"10.1115/sbc2009-206539","title":"Fluid Shear Stress Reduces Simvastatin Induced Adhesion Molecule Expression in Cytokine Activated Endothelial Cells","year":2009,"lang":"en","type":"article","venue":"ASME 2009 Summer Bioengineering Conference, Parts A and B","topic":"Lipoproteins and Cardiovascular Health","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Montreal Heart Institute","funders":"National Research Council Canada; Canadian Institutes of Health Research; National Research Foundation","keywords":"Cell adhesion molecule; Simvastatin; Cell biology; Endothelial stem cell; Intercellular Adhesion Molecule-1; Cell adhesion; VCAM-1; Statin; ICAM-1; E-selectin; Adhesion; Tumor necrosis factor alpha; Chemistry; Soluble cell adhesion molecules; Cytokine; Biology; Cell; Biochemistry; Immunology; Pharmacology; In vitro","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002121453,0.0002874937,0.0004910358,0.0002291247,0.00006476386,0.00005051234,0.00008168252,0.0001675987,0.00005232914],"category_scores_gemma":[0.00002991854,0.0002361958,0.00009682825,0.0002461244,0.00002903882,0.0001255587,0.00003036287,0.0002996178,0.00000822697],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003736856,"about_ca_system_score_gemma":0.0001050314,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001567758,"about_ca_topic_score_gemma":0.000006825848,"domain_scores_codex":[0.9983625,0.00005717606,0.0003502831,0.0004242433,0.0003443741,0.0004614436],"domain_scores_gemma":[0.9992704,0.00002102726,0.00006067576,0.0003153567,0.00007555173,0.0002570068],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001308544,0.0001504849,0.0002255594,0.00007109507,0.00002542756,0.00009119722,0.0002243249,0.00006197386,0.981934,0.00003963089,0.0001263858,0.01691909],"study_design_scores_gemma":[0.001800993,0.0005075677,0.01324074,0.0006572354,0.00003489166,0.00002369126,0.0001292098,0.001161478,0.9805427,0.00001244112,0.001611167,0.0002778356],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9975528,0.0004597767,0.0003931518,0.0003339596,0.0001283306,0.0005251249,0.00003581487,0.00009313691,0.000477866],"genre_scores_gemma":[0.9982953,0.0004354549,0.0007601689,0.0001402965,0.0001806744,0.00002216876,0.00004282805,0.00002490134,0.00009821452],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01664125,"threshold_uncertainty_score":0.9631788,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02208343129516218,"score_gpt":0.2590905965189249,"score_spread":0.2370071652237627,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}