{"id":"W2011098763","doi":"10.1115/sbc2009-206539","title":"Fluid Shear Stress Reduces Simvastatin Induced Adhesion Molecule Expression in Cytokine Activated Endothelial Cells","year":2009,"lang":"en","type":"article","venue":"ASME 2009 Summer Bioengineering Conference, Parts A and B","topic":"Lipoproteins and Cardiovascular Health","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Montreal Heart Institute","funders":"National Research Council Canada; Canadian Institutes of Health Research; National Research Foundation","keywords":"Cell adhesion molecule; Simvastatin; Cell biology; Endothelial stem cell; Intercellular Adhesion Molecule-1; Cell adhesion; VCAM-1; Statin; ICAM-1; E-selectin; Adhesion; Tumor necrosis factor alpha; Chemistry; Soluble cell adhesion molecules; Cytokine; Biology; Cell; Biochemistry; Immunology; Pharmacology; In vitro","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001977303,0.000300988,0.0005241091,0.0003085651,0.0001760819,0.0003144116,0.0001542976,0.0002364837,0.001968317],"category_scores_gemma":[0.0002218314,0.0001163002,0.000352159,0.0002396042,0.0001990964,0.0002176654,0.0001913096,0.0005338709,0.0004045361],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002415483,"about_ca_system_score_gemma":0.000228099,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000738495,"about_ca_topic_score_gemma":0.0007378588,"domain_scores_codex":[0.9997743,0.00004946414,0.00002332802,0.00001937722,0.00006317438,0.00007039255],"domain_scores_gemma":[0.9998652,0.00002555831,0.0000351354,0.00001494666,0.00002734683,0.00003185542],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009184328,0.0001630899,0.0002692532,0.0000704693,0.000008061231,0.00004570519,0.00003189304,0.00005660543,0.995711,0.00005283613,0.0001058266,0.00256681],"study_design_scores_gemma":[0.0001452923,0.004581533,0.01639793,0.0000129623,0.00004385516,0.0001192828,0.0001111516,0.001278619,0.9751971,0.00007198431,0.002030815,0.00000955636],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9946004,0.003331201,0.0007796673,0.0001217594,0.0001070539,0.00002709604,0.0002007447,0.00003889603,0.000793169],"genre_scores_gemma":[0.9931378,0.00239623,0.001119671,0.0001432926,0.00008721501,0.0000692686,0.0005640852,0.00001111108,0.002471248],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001968317,"threshold_uncertainty_score":0.006584704,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02208343129516218,"score_gpt":0.2590905965189249,"score_spread":0.2370071652237627,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}