{"id":"W2011100490","doi":"10.3791/2045","title":"Visualisation and Quantification of Intracellular Interactions of &lt;em&gt;Neisseria meningitidis&lt;/em&gt; and Human &amp;alpha;-actinin by Confocal Imaging","year":2010,"lang":"en","type":"article","venue":"Journal of Visualized Experiments","topic":"Bacterial Infections and Vaccines","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"University of Bristol; Wellcome Trust","keywords":"Cell biology; Cytoskeleton; Confocal microscopy; Endothelial stem cell; Biology; Intracellular; Integrin; Neisseria meningitidis; Bacterial adhesin; Cell culture; Vitronectin; Confocal; Receptor; Cell; Molecular biology; Biophysics; Biochemistry; Bacteria; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000444865,0.0005555043,0.0003462719,0.0006798659,0.0003146797,0.000386593,0.0005781705,0.0009483141,0.001887046],"category_scores_gemma":[0.0002290468,0.0003706179,0.0002731018,0.00045432,0.000422353,0.0003565227,0.0004912527,0.0009255171,0.0005468425],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007794559,"about_ca_system_score_gemma":0.0002860986,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00237735,"about_ca_topic_score_gemma":0.002773551,"domain_scores_codex":[0.9997374,0.00003633351,0.00001802932,0.00007544088,0.00006957606,0.00006322943],"domain_scores_gemma":[0.9997842,0.00007795412,0.00003611962,0.00002448623,0.00004360233,0.0000337186],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004346648,0.00001784775,0.0001167748,0.00005629226,0.000005289366,0.00005788359,0.00003056975,0.00007805284,0.9982322,0.0002241528,0.00006337075,0.001074227],"study_design_scores_gemma":[0.00002099408,0.0001508103,0.01140041,0.00003169225,0.00002379748,0.00057561,0.00008340874,0.006922587,0.977007,0.0001761733,0.003588854,0.00001877703],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9124508,0.003291227,0.07434773,0.0003900137,0.0000574883,0.0001552735,0.001006156,0.0005173596,0.007783936],"genre_scores_gemma":[0.7770503,0.003356006,0.2085072,0.0003249072,0.00004981061,0.0005781528,0.001369097,0.0002285318,0.008535928],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00237735,"threshold_uncertainty_score":0.006312847,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02869824482075664,"score_gpt":0.3841209463902504,"score_spread":0.3554227015694938,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}