{"id":"W2011123535","doi":"10.1074/jbc.m010498200","title":"NADH Oxidase Activity of Mitochondrial Apoptosis-inducing Factor","year":2001,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":385,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Ontario Institute for Cancer Research","funders":"European Commission; Styrelsen för Internationellt Utvecklingssamarbete","keywords":"Apoptosis-inducing factor; Biochemistry; Superoxide; DNA fragmentation; Mitochondrion; Apoptosis; Chemistry; Biology; Molecular biology; Cell biology; Programmed cell death; Enzyme; Caspase","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001128327,0.0001276952,0.0002331902,0.00001684564,0.00003669482,0.000009543289,0.0001643145,0.000316435,0.0001626447],"category_scores_gemma":[0.0001611439,0.00008878718,0.000227992,0.00005659854,0.00006164627,0.000004116833,0.00005818189,0.00015577,8.729994e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001784161,"about_ca_system_score_gemma":0.00004927645,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003247522,"about_ca_topic_score_gemma":3.688971e-7,"domain_scores_codex":[0.9991861,0.00003383044,0.0003167106,0.0001657922,0.0001409698,0.0001565824],"domain_scores_gemma":[0.9992009,0.00002008951,0.0003815432,0.0001552286,0.0001373986,0.0001048628],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003297107,0.0001205657,0.0004977466,0.00001494184,0.00004007539,0.000005454173,0.000006867828,0.00002784159,0.9941441,0.00000213897,0.0001174714,0.004693039],"study_design_scores_gemma":[0.0005386185,0.0002967511,0.001724696,0.00002095686,0.00001322262,0.00007968037,0.00002091711,0.00001535027,0.9930019,0.00004997158,0.004128899,0.0001090787],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971949,0.0002585143,0.001798173,0.00005124233,0.0001922167,0.00004564059,0.000008150169,0.000003395358,0.0004477735],"genre_scores_gemma":[0.997716,0.000290397,0.0008888301,0.000021177,0.0007634489,0.00000102086,0.00001110392,0.000007124258,0.0003009466],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00458396,"threshold_uncertainty_score":0.3620636,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02238824130323447,"score_gpt":0.2567989318549334,"score_spread":0.2344106905516989,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}