{"id":"W2011123535","doi":"10.1074/jbc.m010498200","title":"NADH Oxidase Activity of Mitochondrial Apoptosis-inducing Factor","year":2001,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":385,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Ontario Institute for Cancer Research","funders":"European Commission; Styrelsen för Internationellt Utvecklingssamarbete","keywords":"Apoptosis-inducing factor; Biochemistry; Superoxide; DNA fragmentation; Mitochondrion; Apoptosis; Chemistry; Biology; Molecular biology; Cell biology; Programmed cell death; Enzyme; Caspase","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001636196,0.0004114512,0.0002047869,0.0002442673,0.0001359779,0.0003153293,0.0002422982,0.0002368824,0.0007260827],"category_scores_gemma":[0.0002947811,0.00008912154,0.0002141651,0.0001437414,0.0001219985,0.0002658052,0.0001679817,0.0003124519,0.0002866911],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004447323,"about_ca_system_score_gemma":0.0001485454,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004233585,"about_ca_topic_score_gemma":0.0002194303,"domain_scores_codex":[0.9997914,0.00002427663,0.00001588333,0.0000693625,0.00006638466,0.0000327495],"domain_scores_gemma":[0.9998226,0.00002057218,0.00004207641,0.00002009758,0.00006545013,0.0000293304],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008636417,0.00001201817,0.0006861083,0.00006606367,0.000008448507,0.0000393281,0.00001661114,0.00002010774,0.9947721,0.0001881049,0.00003046065,0.00407422],"study_design_scores_gemma":[0.000007516188,0.00008826063,0.004316957,0.000009939912,0.00001306404,0.000497509,0.00001702506,0.000389685,0.990334,0.0001284082,0.004193449,0.000004150564],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9535562,0.01989467,0.02173794,0.0001760736,0.0001377141,0.00006598366,0.0006507421,0.0001984448,0.003582237],"genre_scores_gemma":[0.9866615,0.00328638,0.005672478,0.00003758569,0.00002273814,0.00003120435,0.001403371,0.00001528734,0.002869459],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007260827,"threshold_uncertainty_score":0.003226697,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02238824130323447,"score_gpt":0.2567989318549334,"score_spread":0.2344106905516989,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}