{"id":"W2011217599","doi":"10.1021/jp9011119","title":"Dendrimers Bind Human Serum Albumin","year":2009,"lang":"fi","type":"article","venue":"The Journal of Physical Chemistry B","topic":"Protein Interaction Studies and Fluorescence Analysis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":219,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université du Québec à Trois-Rivières","funders":"","keywords":"Dendrimer; Macromolecule; Human serum albumin; Chemistry; Circular dichroism; Binding constant; Serum albumin; Biophysics; Random coil; Fluorescence; Stereochemistry; Binding site; Polymer chemistry; Biochemistry; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001391444,0.0004835298,0.0002528004,0.0002144078,0.00020321,0.0002433966,0.0002345364,0.000598719,0.001990331],"category_scores_gemma":[0.0004014177,0.0001583572,0.0002675129,0.000150753,0.0001430978,0.0002346677,0.0003834948,0.0003349916,0.001279274],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005450683,"about_ca_system_score_gemma":0.0001814918,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007623604,"about_ca_topic_score_gemma":0.0004573455,"domain_scores_codex":[0.999797,0.00003103009,0.00001063061,0.0000575674,0.0000564889,0.0000473054],"domain_scores_gemma":[0.9998381,0.00004517664,0.00003596218,0.00001390129,0.00004542757,0.00002131967],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007866678,0.000009501308,0.0002124483,0.00005745601,0.000007264634,0.00002813285,0.00001420442,0.0001283706,0.9968885,0.00006624262,0.0001297737,0.002379568],"study_design_scores_gemma":[0.000008497265,0.0001282962,0.001131251,0.000008465672,0.000009657687,0.0001164926,0.00001055859,0.0007068896,0.9922292,0.00006949803,0.005576534,0.000004596525],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9673811,0.008835291,0.01516691,0.0004790488,0.0001111787,0.0001362302,0.0004537395,0.000438969,0.006997517],"genre_scores_gemma":[0.9679191,0.002537215,0.008417665,0.0004583861,0.00004006824,0.0001034175,0.0007569721,0.00007150366,0.01969577],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001990331,"threshold_uncertainty_score":0.006658256,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008652303468144672,"score_gpt":0.2820372393937512,"score_spread":0.2733849359256065,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}