{"id":"W2011227409","doi":"10.1038/nature03369","title":"Deletion of active ADAMTS5 prevents cartilage degradation in a murine model of osteoarthritis","year":2005,"lang":"en","type":"article","venue":"Nature","topic":"Osteoarthritis Treatment and Mechanisms","field":"Medicine","cited_by":1252,"is_retracted":false,"has_abstract":false,"ca_institutions":"Women's Health Research Institute","funders":"National Institutes of Health; Stryker; Deutsches Krebsforschungszentrum; Howard Hughes Medical Institute","keywords":"Aggrecanase; Aggrecan; ADAMTS; Osteoarthritis; Cartilage; Proteoglycan; Extracellular matrix; Chemistry; Proteases; Cell biology; Pathology; Medicine; Thrombospondin; Articular cartilage; Anatomy; Biology; Biochemistry; Matrix metalloproteinase; Metalloproteinase; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009402182401019449,"score_gpt":0.2582408865680462,"score_spread":0.2488387041670267,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}