{"id":"W2011235873","doi":"10.1089/jir.2012.0010","title":"Individual Interferon Regulatory Factor-3 Thiol Residues Are Not Critical for Its Activation Following Virus Infection","year":2012,"lang":"en","type":"article","venue":"Journal of Interferon & Cytokine Research","topic":"interferon and immune responses","field":"Immunology and Microbiology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Centre Hospitalier de l’Université de Montréal","funders":"Canadian Institutes of Health Research; Institut National de la Santé et de la Recherche Médicale; McMaster University","keywords":"Interferon; Transcription factor; Interferon regulatory factors; Sendai virus; Cell biology; Biology; Phosphorylation; Cysteine; IRF1; Innate immune system; Signal transduction; Chemistry; Biochemistry; Receptor; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001870012,0.0001697401,0.0002251296,0.00007785604,0.0001234206,0.0001733186,0.0001988438,0.0002770826,0.0008152202],"category_scores_gemma":[0.0001996326,0.0001022088,0.0002439777,0.00007291418,0.0001759522,0.0001788002,0.0001423932,0.0003965769,0.0002547012],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000259268,"about_ca_system_score_gemma":0.0001800392,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003763651,"about_ca_topic_score_gemma":0.0004869505,"domain_scores_codex":[0.9998736,0.000022792,0.00001091813,0.00002632632,0.00003048465,0.00003579641],"domain_scores_gemma":[0.9998683,0.00002050691,0.0000394309,0.00002381327,0.0000212171,0.00002675892],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001563212,0.000009953646,0.0003755247,0.00001252763,0.0000034322,0.00002348467,0.000007259775,0.00002738855,0.9988399,0.00003003291,0.000007141378,0.0005069296],"study_design_scores_gemma":[0.000006513873,0.0001308373,0.008409617,0.000003080976,0.00001291674,0.0002344087,0.0000227353,0.0004965644,0.9899455,0.00005425818,0.0006805663,0.000003100604],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997834,0.0005289657,0.00106744,0.00003516818,0.00001389578,0.00001023966,0.00007359726,0.00001436425,0.0004223505],"genre_scores_gemma":[0.998637,0.000156125,0.0005376528,0.00001738664,0.000003638631,0.000008994969,0.0001556102,0.000004312575,0.0004792623],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008152202,"threshold_uncertainty_score":0.002727151,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1362698298193953,"score_gpt":0.411277155637528,"score_spread":0.2750073258181326,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}